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gsk3ba glycogen synthase kinase 3 beta, genome duplicate a [ Danio rerio (zebrafish) ]

Gene ID: 30654, updated on 3-Oct-2019

Summary

Official Symbol
gsk3baprovided by ZNC
Official Full Name
glycogen synthase kinase 3 beta, genome duplicate aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-990714-4
See related
Ensembl:ENSDARG00000017803
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
GSK3; gsk3b; fb68h05; fk80d11; GSK-3[b]; wu:fb68h05; wu:fk80d11
Orthologs

Genomic context

See gsk3ba in Genome Data Viewer
Location:
chromosome: 9
Exon count:
11
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (9577743..9671325, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (9599706..9693358, complement)
103 previous assembly Zv9 (GCF_000002035.4) 9 NC_007120.5 (9800966..9892656, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene MYCBP-associated, testis expressed 1 Neighboring gene nuclear receptor subfamily 1, group I, member 2 Neighboring gene G protein-coupled receptor 156 Neighboring gene leucine rich repeat containing 58b

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
beta-catenin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
tau-protein kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of cell polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extrinsic apoptotic signaling pathway in absence of ligand IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heart jogging IMP
Inferred from Mutant Phenotype
more info
PubMed 
heart looping IMP
Inferred from Mutant Phenotype
more info
PubMed 
insulin receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of dendrite development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptidyl-threonine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
axon IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
beta-catenin destruction complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glutamatergic synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
glycogen synthase kinase-3 beta
NP_571456.1
XP_009302769.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131381.1NP_571456.1  glycogen synthase kinase-3 beta

    See identical proteins and their annotated locations for NP_571456.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ223502
    UniProtKB/TrEMBL
    Q9YH60
    Related
    ENSDARP00000027785.8, ENSDART00000018228.9
    Conserved Domains (2) summary
    cd14137
    Location:51343
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
    pfam00069
    Location:56340
    Pkinase; Protein kinase domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    9577743..9671325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009304494.3XP_009302769.1  glycogen synthase kinase-3 beta isoform X1

    Conserved Domains (2) summary
    cd14137
    Location:51347
    STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3
    pfam00069
    Location:56344
    Pkinase; Protein kinase domain
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