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bmp2b bone morphogenetic protein 2b [ Danio rerio (zebrafish) ]

Gene ID: 30632, updated on 1-Nov-2020

Summary

Official Symbol
bmp2bprovided by ZNC
Official Full Name
bone morphogenetic protein 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-980526-474
See related
Ensembl:ENSDARG00000041430
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
s; swr; bmp2; zbmp; bmp-2; bmp2-; cb670; zbmp-; zbmp2; bmp2-4; zbmp-2
Orthologs

Genomic context

See bmp2b in Genome Data Viewer
Location:
chromosome: 20
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (45893152..45899149)
105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (45989447..45995178)
103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (46426795..46432526, complement)

Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene fermitin family member 1 Neighboring gene uncharacterized LOC108180244 Neighboring gene uncharacterized LOC110438197 Neighboring gene lincRNA 3982

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC92556, MGC136722

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
BMP receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
growth factor activity IEA
Inferred from Electronic Annotation
more info
 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
BMP signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
BMP signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
SMAD protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell migration involved in gastrulation IGI
Inferred from Genetic Interaction
more info
PubMed 
cell-cell signaling involved in cell fate commitment IMP
Inferred from Mutant Phenotype
more info
 
determination of left/right symmetry IMP
Inferred from Mutant Phenotype
more info
PubMed 
determination of ventral identity IDA
Inferred from Direct Assay
more info
PubMed 
determination of ventral identity IGI
Inferred from Genetic Interaction
more info
PubMed 
determination of ventral identity IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal convergence IDA
Inferred from Direct Assay
more info
PubMed 
dorsal convergence IGI
Inferred from Genetic Interaction
more info
PubMed 
dorsal/ventral axis specification IMP
Inferred from Mutant Phenotype
more info
PubMed 
dorsal/ventral pattern formation IDA
Inferred from Direct Assay
more info
PubMed 
dorsal/ventral pattern formation IEP
Inferred from Expression Pattern
more info
 
dorsal/ventral pattern formation IGI
Inferred from Genetic Interaction
more info
PubMed 
dorsal/ventral pattern formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
embryonic viscerocranium morphogenesis IGI
Inferred from Genetic Interaction
more info
PubMed 
embryonic viscerocranium morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
hypoblast development IMP
Inferred from Mutant Phenotype
more info
 
liver development IMP
Inferred from Mutant Phenotype
more info
PubMed 
locus ceruleus development IMP
Inferred from Mutant Phenotype
more info
PubMed 
mesodermal cell fate commitment IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of endodermal cell fate specification IGI
Inferred from Genetic Interaction
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neurogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
notochord development IGI
Inferred from Genetic Interaction
more info
PubMed 
pancreas field specification IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of BMP signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of pathway-restricted SMAD protein phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein-containing complex assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
semicircular canal formation IMP
Inferred from Mutant Phenotype
more info
PubMed 
semicircular canal morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
ventricular cardiac muscle cell development IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
bone morphogenetic protein 2b
Names
etID309839.20
swirl

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131360.2NP_571435.1  bone morphogenetic protein 2b precursor

    See identical proteins and their annotated locations for NP_571435.1

    Status: VALIDATED

    Source sequence(s)
    AL929237, BC114256
    UniProtKB/TrEMBL
    O93369
    Related
    ENSDARP00000107417.2, ENSDART00000131169.4
    Conserved Domains (2) summary
    pfam00688
    Location:49276
    TGFb_propeptide; TGF-beta propeptide
    cd13760
    Location:311411
    TGF_beta_BMP2_like; transforming growth factor beta (TGF-beta) like domain found in bone morphogenetic protein 2 (BMP-2), 4 (BMP-4) and similar proteins

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007131.7 Reference GRCz11 Primary Assembly

    Range
    45893152..45899149
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395076.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    39751..45748
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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