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Haus4 HAUS augmin-like complex, subunit 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 305882, updated on 5-Jan-2022

Summary

Official Symbol
Haus4provided by RGD
Official Full Name
HAUS augmin-like complex, subunit 4provided by RGD
Primary source
RGD:1305288
See related
Ensembl:ENSRNOG00000039284
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305288
Summary
Predicted to enable microtubule minus-end binding activity. Predicted to be involved in centrosome cycle and spindle assembly. Predicted to be located in centrosome and mitotic spindle microtubule. Predicted to be part of HAUS complex. Orthologous to human HAUS4 (HAUS augmin like complex subunit 4). [provided by Alliance of Genome Resources, Nov 2021]
Expression
Biased expression in Thymus (RPKM 118.2), Testes (RPKM 98.4) and 9 other tissues See more
Orthologs
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Genomic context

See Haus4 in Genome Data Viewer
Location:
15p13
Exon count:
11
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (27994530..28006147, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (33182139..33193880, complement)

Chromosome 15 - NC_051350.1Genomic Context describing neighboring genes Neighboring gene protein arginine methyltransferase 5 Neighboring gene transfer RNA arginine (anticodon ACG) Neighboring gene ajuba LIM protein Neighboring gene similar to RIKEN cDNA 4931414P19

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables microtubule minus-end binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in centrosome cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in centrosome cycle ISO
Inferred from Sequence Orthology
more info
 
involved_in spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in spindle assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
part_of HAUS complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of HAUS complex ISO
Inferred from Sequence Orthology
more info
 
located_in centrosome ISO
Inferred from Sequence Orthology
more info
 
located_in mitotic spindle microtubule ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
HAUS augmin-like complex subunit 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013995.1NP_001014017.1  HAUS augmin-like complex subunit 4

    See identical proteins and their annotated locations for NP_001014017.1

    Status: PROVISIONAL

    Source sequence(s)
    BC079109
    UniProtKB/TrEMBL
    Q6AYC0
    Related
    ENSRNOP00000016401.6, ENSRNOT00000016401.8
    Conserved Domains (1) summary
    pfam14735
    Location:126360
    HAUS4; HAUS augmin-like complex subunit 4

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051350.1 Reference mRatBN7.2 Primary Assembly

    Range
    27994530..28006147 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006251955.3XP_006252017.1  HAUS augmin-like complex subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006252017.1

    UniProtKB/TrEMBL
    Q6AYC0
    Conserved Domains (1) summary
    pfam14735
    Location:126360
    HAUS4; HAUS augmin-like complex subunit 4
  2. XM_006251956.4XP_006252018.1  HAUS augmin-like complex subunit 4 isoform X1

    See identical proteins and their annotated locations for XP_006252018.1

    UniProtKB/TrEMBL
    Q6AYC0
    Conserved Domains (1) summary
    pfam14735
    Location:126360
    HAUS4; HAUS augmin-like complex subunit 4
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