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Atg14 autophagy related 14 [ Rattus norvegicus (Norway rat) ]

Gene ID: 305831, updated on 30-Sep-2021

Summary

Symbol
Atg14provided by RGD
Full Name
autophagy related 14provided by RGD
Primary source
RGD:1304610
See related
EnsemblRapid:ENSRNOG00000011873
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Atg14L; RGD1304610
Expression
Biased expression in Adrenal (RPKM 40.0), Kidney (RPKM 38.2) and 9 other tissues See more
Orthologs
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Genomic context

See Atg14 in Genome Data Viewer
Location:
15p14
Exon count:
10
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (20795750..20827113, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (24343418..24374776, complement)

Chromosome 15 - NC_051350.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120096955 Neighboring gene uncharacterized LOC120096954 Neighboring gene F-box protein 34 Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC108352900 Neighboring gene ATP synthase subunit d, mitochondrial-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTPase binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in autophagosome assembly ISO
Inferred from Sequence Orthology
more info
 
involved_in autophagosome membrane docking ISO
Inferred from Sequence Orthology
more info
 
involved_in autophagy ISO
Inferred from Sequence Orthology
more info
 
involved_in biological_process ND
No biological Data available
more info
 
involved_in cellular response to glucose starvation ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular response to glucose starvation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in cellular response to starvation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to starvation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within endosome to lysosome transport ISO
Inferred from Sequence Orthology
more info
 
involved_in macroautophagy ISO
Inferred from Sequence Orthology
more info
 
involved_in mitophagy IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in mitophagy ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in negative regulation of protein phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in positive regulation of phosphatidylinositol 3-kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase activity ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
involved_in positive regulation of protein phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in posttranscriptional regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of protein phosphorylation ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within regulation of triglyceride metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in response to mitochondrial depolarisation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in autophagosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in autophagosome ISO
Inferred from Sequence Orthology
more info
 
located_in axoneme ISO
Inferred from Sequence Orthology
more info
 
located_in axoneme ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in cellular_component ND
No biological Data available
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in extrinsic component of omegasome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extrinsic component of omegasome membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in extrinsic component of phagophore assembly site membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extrinsic component of phagophore assembly site membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in mitochondria-associated endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondria-associated endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in phagocytic vesicle ISO
Inferred from Sequence Orthology
more info
 
located_in phagophore assembly site membrane ISO
Inferred from Sequence Orthology
more info
 
part_of phosphatidylinositol 3-kinase complex, class III IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of phosphatidylinositol 3-kinase complex, class III ISO
Inferred from Sequence Orthology
more info
 
part_of phosphatidylinositol 3-kinase complex, class III ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
beclin 1-associated autophagy-related key regulator
Names
ATG14 autophagy related 14 homolog
autophagy-related protein 14-like protein
barkor
beclin 1-associated autophagy-related key regulator-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107258.1NP_001100728.1  beclin 1-associated autophagy-related key regulator

    See identical proteins and their annotated locations for NP_001100728.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474040
    UniProtKB/Swiss-Prot
    D4A4K3
    Related
    ENSRNOP00000016274.3, ENSRNOT00000016274.5
    Conserved Domains (1) summary
    pfam10186
    Location:43378
    Atg14; Vacuolar sorting 38 and autophagy-related subunit 14

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051350.1 Reference mRatBN7.2 Primary Assembly

    Range
    20795750..20827113 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_005493716.1 RNA Sequence

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