Gbp6 guanylate binding protein family member 6 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Gbp6provided by RGD
Official Full Name: guanylate binding protein family member 6provided by RGD
Primary source: RGD:1561523
See related: Ensembl:ENSRNOG00000068418 AllianceGenome:RGD:1561523
Gene type: protein coding
RefSeq status: MODEL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Mpa2l; RGD1561523
Summary: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in cellular response to interferon-gamma; defense response to Gram-positive bacterium; and defense response to protozoan. Predicted to be active in cytoplasmic vesicle. Orthologous to human GBP6 (guanylate binding protein family member 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Spleen (RPKM 159.8), Adrenal (RPKM 96.0) and 8 other tissues See more
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Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (5034999..5062023)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (4730286..4756508)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (5927568..5954923)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables GTP binding	IBA Inferred from Biological aspect of Ancestor more info
enables GTPase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within adhesion of symbiont to host	ISO Inferred from Sequence Orthology more info
involved_in cellular response to type II interferon	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within cellular response to type II interferon	ISO Inferred from Sequence Orthology more info
involved_in defense response to Gram-positive bacterium	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within defense response to Gram-positive bacterium	ISO Inferred from Sequence Orthology more info
involved_in defense response to protozoan	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within defense response to protozoan	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasmic vesicle	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasmic vesicle	ISO Inferred from Sequence Orthology more info