Format

Send to:

Choose Destination

Klf1 Kruppel like factor 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304666, updated on 12-Aug-2018

Summary

Official Symbol
Klf1provided by RGD
Official Full Name
Kruppel like factor 1provided by RGD
Primary source
RGD:1309398
See related
Ensembl:ENSRNOG00000003443
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Spleen (RPKM 271.7) and Lung (RPKM 11.0) See more
Orthologs

Genomic context

See Klf1 in Genome Data Viewer
Location:
19q11
Exon count:
3
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (26016289..26019557)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 19 NC_005118.3 (36991935..36995180)

Chromosome 19 - NC_005118.4Genomic Context describing neighboring genes Neighboring gene phenylalanyl-tRNA synthetase subunit alpha Neighboring gene synaptonemal complex central element protein 2 Neighboring gene glutaryl-CoA dehydrogenase Neighboring gene deoxyribonuclease 2, lysosomal Neighboring gene microtubule associated serine/threonine kinase 1 Neighboring gene microRNA 3550

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
cellular response to peptide IEP
Inferred from Expression Pattern
more info
PubMed 
chromatin remodeling ISO
Inferred from Sequence Orthology
more info
 
embryonic hemopoiesis ISO
Inferred from Sequence Orthology
more info
 
erythrocyte development ISO
Inferred from Sequence Orthology
more info
 
erythrocyte differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
erythrocyte differentiation IEA
Inferred from Electronic Annotation
more info
 
erythrocyte differentiation ISO
Inferred from Sequence Orthology
more info
 
erythrocyte maturation ISO
Inferred from Sequence Orthology
more info
 
in utero embryonic development ISO
Inferred from Sequence Orthology
more info
 
liver development ISO
Inferred from Sequence Orthology
more info
 
maternal process involved in female pregnancy IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
nuclear chromatin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear chromatin IEA
Inferred from Electronic Annotation
more info
 
nuclear chromatin ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
Krueppel-like factor 1
Names
Kruppel-like factor 1 (erythroid)
erythroid Kruppel-like factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107164.1NP_001100634.1  Krueppel-like factor 1

    See identical proteins and their annotated locations for NP_001100634.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473972
    UniProtKB/TrEMBL
    G3V6F3
    Related
    ENSRNOP00000004601.5, ENSRNOT00000004601.5
    Conserved Domains (6) summary
    COG5048
    Location:297375
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:298317
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:293317
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:339364
    zf-H2C2_2; Zinc-finger double domain
    pfam16832
    Location:4065
    EKLF_TAD1; Erythroid krueppel-like transcription factor, transactivation 1
    pfam16833
    Location:81103
    EKLF_TAD2; Erythroid krueppel-like transcription factor, transactivation 2

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005118.4 Reference Rnor_6.0 Primary Assembly

    Range
    26016289..26019557
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006255254.3XP_006255316.1  Krueppel-like factor 1 isoform X1

    Conserved Domains (6) summary
    COG5048
    Location:297380
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:298317
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:293317
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:344369
    zf-H2C2_2; Zinc-finger double domain
    pfam16832
    Location:4065
    EKLF_TAD1; Erythroid krueppel-like transcription factor, transactivation 1
    pfam16833
    Location:81103
    EKLF_TAD2; Erythroid krueppel-like transcription factor, transactivation 2

Alternate Rn_Celera

Genomic

  1. AC_000087.1 Alternate Rn_Celera

    Range
    22807529..22810700 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center