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Klf1 Kruppel like factor 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 304666, updated on 30-Sep-2021

Summary

Official Symbol
Klf1provided by RGD
Official Full Name
Kruppel like factor 1provided by RGD
Primary source
RGD:1309398
See related
EnsemblRapid:ENSRNOG00000003443
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Spleen (RPKM 271.7) and Lung (RPKM 11.0) See more
Orthologs
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Genomic context

See Klf1 in Genome Data Viewer
Location:
19q11
Exon count:
3
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (23250627..23253802, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (26016289..26019557)

Chromosome 19 - NC_051354.1Genomic Context describing neighboring genes Neighboring gene microtubule associated serine/threonine kinase 1 Neighboring gene microRNA 3550 Neighboring gene deoxyribonuclease 2, lysosomal Neighboring gene glutaryl-CoA dehydrogenase Neighboring gene synaptonemal complex central element protein 2 Neighboring gene phenylalanyl-tRNA synthetase subunit alpha

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in chromatin ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
Krueppel-like factor 1
Names
Kruppel-like factor 1 (erythroid)
erythroid Kruppel-like factor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107164.1NP_001100634.1  Krueppel-like factor 1

    See identical proteins and their annotated locations for NP_001100634.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473972
    UniProtKB/TrEMBL
    G3V6F3
    Related
    ENSRNOP00000004601.6, ENSRNOT00000004601.6
    Conserved Domains (6) summary
    COG5048
    Location:297375
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:298317
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:293317
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:339364
    zf-H2C2_2; Zinc-finger double domain
    pfam16832
    Location:4065
    EKLF_TAD1; Erythroid krueppel-like transcription factor, transactivation 1
    pfam16833
    Location:81103
    EKLF_TAD2; Erythroid krueppel-like transcription factor, transactivation 2

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051354.1 Reference mRatBN7.2 Primary Assembly

    Range
    23250627..23253802 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006255254.4XP_006255316.1  Krueppel-like factor 1 isoform X1

    Conserved Domains (6) summary
    COG5048
    Location:297380
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:298317
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:293317
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:344369
    zf-H2C2_2; Zinc-finger double domain
    pfam16832
    Location:4065
    EKLF_TAD1; Erythroid krueppel-like transcription factor, transactivation 1
    pfam16833
    Location:81103
    EKLF_TAD2; Erythroid krueppel-like transcription factor, transactivation 2
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