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Ets2 ETS proto-oncogene 2, transcription factor [ Rattus norvegicus (Norway rat) ]

Gene ID: 304063, updated on 18-Nov-2018

Summary

Official Symbol
Ets2provided by RGD
Official Full Name
ETS proto-oncogene 2, transcription factorprovided by RGD
Primary source
RGD:1584977
See related
Ensembl:ENSRNOG00000001647
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Lung (RPKM 155.5), Kidney (RPKM 147.4) and 9 other tissues See more
Orthologs

Genomic context

See Ets2 in Genome Data Viewer
Location:
11q11
Exon count:
11
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 11 NC_005110.4 (36075709..36092495)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 11 NC_005110.3 (39606999..39623785)

Chromosome 11 - NC_005110.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102550135 Neighboring gene potassium voltage-gated channel subfamily J member 15 Neighboring gene ETS transcription factor ERG Neighboring gene uncharacterized LOC103693523 Neighboring gene uncharacterized LOC108352314

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Process Evidence Code Pubs
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ectodermal cell fate commitment IEA
Inferred from Electronic Annotation
more info
 
ectodermal cell fate commitment ISO
Inferred from Sequence Orthology
more info
 
mesoderm development IEA
Inferred from Electronic Annotation
more info
 
mesoderm development ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription by RNA polymerase II IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
primitive streak formation IEA
Inferred from Electronic Annotation
more info
 
primitive streak formation ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytosol IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein C-ets-2
Names
E26 avian leukemia oncogene 2, 3' domain
avian erythroblastosis virus E26 (v-ets) oncogene homolog 2
v-ets avian erythroblastosis virus E26 oncogene homolog 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001107107.1NP_001100577.2  protein C-ets-2

    See identical proteins and their annotated locations for NP_001100577.2

    Status: PROVISIONAL

    Source sequence(s)
    AC097832
    UniProtKB/TrEMBL
    D4AAH4
    Related
    ENSRNOP00000002247.4, ENSRNOT00000002247.6
    Conserved Domains (2) summary
    cd08543
    Location:85173
    SAM_PNT-ETS-2; Sterile alpha motif (SAM)/Pointed domain of ETS-2
    smart00413
    Location:363447
    ETS; erythroblast transformation specific domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005110.4 Reference Rnor_6.0 Primary Assembly

    Range
    36075709..36092495
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006248177.2XP_006248239.1  protein C-ets-2 isoform X1

    Conserved Domains (2) summary
    cd08543
    Location:109197
    SAM_PNT-ETS-2; Sterile alpha motif (SAM)/Pointed domain of ETS-2
    smart00413
    Location:387471
    ETS; erythroblast transformation specific domain

Alternate Rn_Celera

Genomic

  1. AC_000079.1 Alternate Rn_Celera

    Range
    33421839..33438625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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