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Pipox pipecolic acid and sarcosine oxidase [ Rattus norvegicus (Norway rat) ]

Gene ID: 303272, updated on 18-Apr-2019

Summary

Official Symbol
Pipoxprovided by RGD
Official Full Name
pipecolic acid and sarcosine oxidaseprovided by RGD
Primary source
RGD:1311347
See related
Ensembl:ENSRNOG00000008798
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Liver (RPKM 377.1), Adrenal (RPKM 76.1) and 1 other tissue See more
Orthologs

Genomic context

See Pipox in Genome Data Viewer
Location:
10q25
Exon count:
9
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (64951986..64964865)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (66660848..66673727, complement)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene PHD finger protein 12 Neighboring gene seizure related 6 homolog Neighboring gene uncharacterized LOC102551552 Neighboring gene uncharacterized LOC103693392 Neighboring gene uncharacterized LOC102557169 Neighboring gene myosin XVIIIa Neighboring gene basic salivary proline-rich protein 2-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
L-pipecolate oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
L-pipecolate oxidase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
sarcosine oxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sarcosine oxidase activity ISO
Inferred from Sequence Orthology
more info
PubMed 
signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 
signaling receptor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
L-lysine catabolic process to acetyl-CoA via L-pipecolate IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
L-lysine catabolic process to acetyl-CoA via L-pipecolate ISO
Inferred from Sequence Orthology
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process ISO
Inferred from Sequence Orthology
more info
PubMed 
tetrahydrofolate metabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
peroxisome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peroxisome ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
peroxisomal sarcosine oxidase
Names
pipecolic acid oxidase
NP_001012009.1
XP_006247020.1
XP_006247021.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012009.1NP_001012009.1  peroxisomal sarcosine oxidase

    See identical proteins and their annotated locations for NP_001012009.1

    Status: PROVISIONAL

    Source sequence(s)
    BC088249
    UniProtKB/TrEMBL
    Q5I0K1
    Related
    ENSRNOP00000012154.4, ENSRNOT00000012154.7
    Conserved Domains (2) summary
    TIGR01377
    Location:8388
    soxA_mon; sarcosine oxidase, monomeric form
    cl21454
    Location:868
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    64951986..64964865
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006246958.1XP_006247020.1  peroxisomal sarcosine oxidase isoform X2

    See identical proteins and their annotated locations for XP_006247020.1

    UniProtKB/TrEMBL
    Q5I0K1
    Conserved Domains (2) summary
    TIGR01377
    Location:8388
    soxA_mon; sarcosine oxidase, monomeric form
    cl21454
    Location:868
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
  2. XM_006246959.2XP_006247021.1  peroxisomal sarcosine oxidase isoform X1

    Conserved Domains (2) summary
    TIGR01377
    Location:8335
    soxA_mon; sarcosine oxidase, monomeric form
    cl21454
    Location:868
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    61749538..61762034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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