Format

Send to:

Choose Destination

Rab11fip3 RAB11 family interacting protein 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 303002, updated on 18-Apr-2019

Summary

Official Symbol
Rab11fip3provided by RGD
Official Full Name
RAB11 family interacting protein 3provided by RGD
Primary source
RGD:1308952
Gene type
protein coding
RefSeq status
MODEL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
LRRGT00043; RGD1308952
Expression
Biased expression in Kidney (RPKM 349.4), Brain (RPKM 75.3) and 9 other tissues See more
Orthologs

Genomic context

See Rab11fip3 in Genome Data Viewer
Location:
10q12
Exon count:
15
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (15348356..15433384, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (15162587..15246355, complement)

Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L36a-like Neighboring gene calpain 15 Neighboring gene 60S ribosomal protein L34 pseudogene Neighboring gene putative 60S ribosomal protein L37a-like Neighboring gene 60S ribosomal protein L3-like Neighboring gene 2,4-dienoyl-CoA reductase 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

  • Endocytosis, organism-specific biosystem (from KEGG)
    Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
  • Endocytosis, conserved biosystem (from KEGG)
    Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ADP-ribosylation factor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
Rab GTPase binding ISO
Inferred from Sequence Orthology
more info
PubMed 
dynein light intermediate chain binding ISO
Inferred from Sequence Orthology
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
PubMed 
Process Evidence Code Pubs
endocytic recycling ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of adiponectin secretion ISO
Inferred from Sequence Orthology
more info
PubMed 
protein localization to cilium ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of cytokinesis ISO
Inferred from Sequence Orthology
more info
PubMed 
Component Evidence Code Pubs
centrosome ISO
Inferred from Sequence Orthology
more info
PubMed 
cleavage furrow ISO
Inferred from Sequence Orthology
more info
PubMed 
endosome ISO
Inferred from Sequence Orthology
more info
PubMed 
intercellular bridge ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
microtubule organizing center ISO
Inferred from Sequence Orthology
more info
 
midbody ISO
Inferred from Sequence Orthology
more info
PubMed 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
recycling endosome ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
rab11 family-interacting protein 3
Names
RAB11 family interacting protein 3 (class II)
eferin
XP_001062691.2
XP_002724708.1
XP_002727801.1
XP_006220676.1
XP_006246133.1
XP_220262.5

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

    Range
    15348356..15433384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006246071.2XP_006246133.1  rab11 family-interacting protein 3 isoform X3

    See identical proteins and their annotated locations for XP_006246133.1

    Conserved Domains (7) summary
    cd00051
    Location:516573
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam09457
    Location:10131053
    RBD-FIP; FIP domain
    pfam05700
    Location:776886
    BCAS2; Breast carcinoma amplified sequence 2 (BCAS2)
    pfam07926
    Location:837985
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam13499
    Location:517573
    EF-hand_7; EF-hand domain pair
    pfam14077
    Location:944987
    WD40_alt; Alternative WD40 repeat motif
    cl00143
    Location:837939
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
  2. XM_002727755.4XP_002727801.1  rab11 family-interacting protein 3 isoform X2

    See identical proteins and their annotated locations for XP_002727801.1

    Conserved Domains (7) summary
    cd00051
    Location:516573
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam09457
    Location:10251065
    RBD-FIP; FIP domain
    pfam05700
    Location:788898
    BCAS2; Breast carcinoma amplified sequence 2 (BCAS2)
    pfam07926
    Location:849997
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam13499
    Location:517573
    EF-hand_7; EF-hand domain pair
    pfam14077
    Location:956999
    WD40_alt; Alternative WD40 repeat motif
    cl00143
    Location:849951
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
  3. XM_220262.7XP_220262.5  rab11 family-interacting protein 3 isoform X1

    See identical proteins and their annotated locations for XP_220262.5

    Conserved Domains (7) summary
    cd00051
    Location:516573
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam09457
    Location:10701110
    RBD-FIP; FIP domain
    pfam05700
    Location:833943
    BCAS2; Breast carcinoma amplified sequence 2 (BCAS2)
    pfam07926
    Location:8941042
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam13499
    Location:517573
    EF-hand_7; EF-hand domain pair
    pfam14077
    Location:10011044
    WD40_alt; Alternative WD40 repeat motif
    cl00143
    Location:894996
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...

Alternate Rn_Celera

Genomic

  1. AC_000078.1 Alternate Rn_Celera

    Range
    14670109..14755010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006220614.3XP_006220676.1  rab11 family-interacting protein 3 isoform X3

    See identical proteins and their annotated locations for XP_006220676.1

    Conserved Domains (7) summary
    cd00051
    Location:516573
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam09457
    Location:10131053
    RBD-FIP; FIP domain
    pfam05700
    Location:776886
    BCAS2; Breast carcinoma amplified sequence 2 (BCAS2)
    pfam07926
    Location:837985
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam13499
    Location:517573
    EF-hand_7; EF-hand domain pair
    pfam14077
    Location:944987
    WD40_alt; Alternative WD40 repeat motif
    cl00143
    Location:837939
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
  2. XM_002724662.5XP_002724708.1  rab11 family-interacting protein 3 isoform X2

    See identical proteins and their annotated locations for XP_002724708.1

    Conserved Domains (7) summary
    cd00051
    Location:516573
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam09457
    Location:10251065
    RBD-FIP; FIP domain
    pfam05700
    Location:788898
    BCAS2; Breast carcinoma amplified sequence 2 (BCAS2)
    pfam07926
    Location:849997
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam13499
    Location:517573
    EF-hand_7; EF-hand domain pair
    pfam14077
    Location:956999
    WD40_alt; Alternative WD40 repeat motif
    cl00143
    Location:849951
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
  3. XM_001062691.5XP_001062691.2  rab11 family-interacting protein 3 isoform X1

    See identical proteins and their annotated locations for XP_001062691.2

    Conserved Domains (7) summary
    cd00051
    Location:516573
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam09457
    Location:10701110
    RBD-FIP; FIP domain
    pfam05700
    Location:833943
    BCAS2; Breast carcinoma amplified sequence 2 (BCAS2)
    pfam07926
    Location:8941042
    TPR_MLP1_2; TPR/MLP1/MLP2-like protein
    pfam13499
    Location:517573
    EF-hand_7; EF-hand domain pair
    pfam14077
    Location:10011044
    WD40_alt; Alternative WD40 repeat motif
    cl00143
    Location:894996
    SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
Support Center