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nr1d2b nuclear receptor subfamily 1, group D, member 2b [ Danio rerio (zebrafish) ]

Gene ID: 30271, updated on 3-Oct-2019

Summary

Official Symbol
nr1d2bprovided by ZNC
Official Full Name
nuclear receptor subfamily 1, group D, member 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-990415-244
See related
Ensembl:ENSDARG00000009594
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
Also known as
reverbb; reverbb2; zgc:92019
Orthologs

Genomic context

See nr1d2b in Genome Data Viewer
Location:
chromosome: 19
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (17400261..17407462)
105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (17941690..17948550)
103 previous assembly Zv9 (GCF_000002035.4) 19 NC_007130.5 (19388547..19395415)

Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene NFKB inhibitor interacting Ras-like 1 Neighboring gene ribosomal protein L15 Neighboring gene uncharacterized LOC110438144 Neighboring gene thyroid hormone receptor beta

Genomic regions, transcripts, and products

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
RNA polymerase II regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nuclear receptor transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
signaling receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
steroid hormone receptor activity IEA
Inferred from Electronic Annotation
more info
 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
hormone-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of circadian rhythm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to lipid IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
RNA polymerase II transcription factor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
nuclear receptor subfamily 1 group D member 2
Names
NR1D2-B
Rev-Erb beta 2
rev erb beta 2
rev-erb-beta

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131065.1NP_571140.1  nuclear receptor subfamily 1 group D member 2

    See identical proteins and their annotated locations for NP_571140.1

    Status: PROVISIONAL

    Source sequence(s)
    BC074065
    UniProtKB/TrEMBL
    Q6GMI3
    Related
    ENSDARP00000112360.1, ENSDART00000127353.2
    Conserved Domains (2) summary
    cd06940
    Location:388576
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cd07166
    Location:81169
    NR_DBD_REV_ERB; DNA-binding domain of REV-ERB receptor-like is composed of two C4-type zinc fingers

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007130.7 Reference GRCz11 Primary Assembly

    Range
    17400261..17407462
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005159500.4XP_005159557.1  nuclear receptor subfamily 1 group D member 2 isoform X1

    Conserved Domains (2) summary
    cd06940
    Location:308496
    NR_LBD_REV_ERB; The ligand binding domain of REV-ERB receptors, members of the nuclear receptor superfamily
    cl02596
    Location:2789
    NR_DBD_like; DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers
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