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Satl1 spermidine/spermine N1-acetyl transferase-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 302325, updated on 8-Apr-2026
Official Symbol
Satl1provided by RGD
Official Full Name
spermidine/spermine N1-acetyl transferase-like 1provided by RGD
Primary source
RGD:1565932
See related
Ensembl:ENSRNOG00000022476 AllianceGenome:RGD:1565932
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1565932
Summary
Predicted to enable diamine N-acetyltransferase activity and spermidine binding activity. Predicted to be involved in spermidine acetylation. Orthologous to human SATL1 (spermidine/spermine N1-acetyl transferase like 1). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Testes (RPKM 37.4), Muscle (RPKM 4.1) and 4 other tissues See more
Orthologs
all
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Try the new Transcripts and proteins table
See Satl1 in Genome Data Viewer
Location:
Xq31
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (81645584..81661393, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (77453357..77469100, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (83772526..83788556, complement)

Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene testis expressed gene 16 Neighboring gene ubiquitin-conjugating enzyme E2D 4 like 1 Neighboring gene apolipoprotein O-like Neighboring gene RIKEN cDNA 2010106E10 gene like Neighboring gene eukaryotic translation elongation factor 1 alpha 1, pseudogene 18

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
Inferred from Electronic Annotation
more info
  
enables diamine N-acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables spermidine binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in polyamine metabolic process IEA
Inferred from Electronic Annotation
more info
  
involved_in spermidine acetylation IBA
Inferred from Biological aspect of Ancestor
more info
  
Preferred Names
spermidine/spermine N(1)-acetyltransferase-like protein 1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163543.1 → NP_001157015.1  spermidine/spermine N(1)-acetyltransferase-like protein 1

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000021
    UniProtKB/TrEMBL
    A6IV98, D3ZA19
    Related
    ENSRNOP00000034830.4, ENSRNOT00000037149.7
    Conserved Domains (2) summary
    COG0456
    Location:594 → 731
    RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]
    pfam00583
    Location:657 → 731
    Acetyltransf_1; Acetyltransferase (GNAT) family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086039.1 Reference GRCr8

    Range
    81645584..81661393 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063279890.1 → XP_063135960.1  spermidine/spermine N(1)-acetyltransferase-like protein 1 isoform X3

    UniProtKB/TrEMBL
    A6IV98

  2. XM_039099582.2 → XP_038955510.2  spermidine/spermine N(1)-acetyltransferase-like protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZV75, A6IV98
    Related
    ENSRNOP00000082605.2, ENSRNOT00000106441.2

  3. XM_063279889.1 → XP_063135959.1  spermidine/spermine N(1)-acetyltransferase-like protein 1 isoform X2

    UniProtKB/TrEMBL
    A0ABK0L7K0, A6IV98
    Related
    ENSRNOP00000100069.1, ENSRNOT00000144938.1
Nucleotide Protein Strain
Heading Accession and Version

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