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egr2b early growth response 2b [ Danio rerio (zebrafish) ]

Gene ID: 30190, updated on 19-Sep-2021

Summary

Official Symbol
egr2bprovided by ZNC
Official Full Name
early growth response 2bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-980526-283
See related
Ensembl:ENSDARG00000042826
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
egr; egr2; krox; krx2; cb427; krox-; krx20; KRX-20; krox20; id:ibd50; zgc:92210; id:ibd5073; wu:fb71h10
Orthologs
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Genomic context

See egr2b in Genome Data Viewer
Location:
chromosome: 12
Exon count:
3
Annotation release Status Assembly Chr Location
106 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (8483834..8504291, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (8445995..8448484, complement)
103 previous assembly Zv9 (GCF_000002035.4) 12 NC_007123.5 (9238036..9258480, complement)

Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene AT-rich interaction domain 5B Neighboring gene 2-aminoethanethiol (cysteamine) dioxygenase a Neighboring gene nuclear receptor binding factor 2b Neighboring gene jumonji domain containing 1Cb

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC92210

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
early growth response protein 2b
Names
EGR-2b
krox-20
protein krx-20
zinc finger protein Krox-20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_130997.2NP_571072.2  early growth response protein 2b

    See identical proteins and their annotated locations for NP_571072.2

    Status: PROVISIONAL

    Source sequence(s)
    BC081622
    UniProtKB/TrEMBL
    Q66HY5
    Related
    ENSDARP00000062854.4, ENSDART00000062855.5
    Conserved Domains (5) summary
    COG5048
    Location:327411
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:301323
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:299323
    zf-C2H2; Zinc finger, C2H2 type
    pfam11928
    Location:92164
    DUF3446; Domain of unknown function (DUF3446)
    pfam13465
    Location:343368
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007123.7 Reference GRCz11 Primary Assembly

    Range
    8483834..8504291 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021480019.1XP_021335694.1  early growth response protein 2b isoform X1

    Conserved Domains (4) summary
    COG5048
    Location:266350
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:240262
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam11928
    Location:31103
    DUF3446; Domain of unknown function (DUF3446)
    pfam13465
    Location:282307
    zf-H2C2_2; Zinc-finger double domain
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