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Foxn2 forkhead box N2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 301676, updated on 6-Jul-2026
Official Symbol
Foxn2provided by RGD
Official Full Name
forkhead box N2provided by RGD
Primary source
RGD:1562291
See related
Ensembl:ENSRNOG00000040110 AllianceGenome:RGD:1562291
Gene type
protein coding
RefSeq status
INFERRED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1562291
Summary
Predicted to enable DNA-binding transcription factor activity and cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within skeletal muscle cell differentiation. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to human FOXN2 (forkhead box N2). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Spleen (RPKM 180.3), Thymus (RPKM 172.5) and 9 other tissues See more
Orthologs
all
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Try the new Transcripts and proteins table
See Foxn2 in Genome Data Viewer
Location:
6q12
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (11772180..11818751, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (6018653..6065226, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene protein phosphatase 1, regulatory subunit 21 Neighboring gene uncharacterized LOC102546644 Neighboring gene uncharacterized LOC134479302 Neighboring gene uncharacterized LOC120103456 Neighboring gene nuclear cap-binding protein subunit 2 pseudogene

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Analysis of early C2C12 myogenesis identifies stably and differentially expressed transcriptional regulators whose knock-down inhibits myoblast differentiation. Rajan S, et al. Physiol Genomics, 2012 Feb 1. PMID 22147266
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
  
enables cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific double-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables sequence-specific double-stranded DNA binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within skeletal muscle cell differentiation ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
forkhead box protein N2

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001399771.1 → NP_001386700.1  forkhead box protein N2

    Status: INFERRED

    Source sequence(s)
    JAXUCZ010000006
    UniProtKB/TrEMBL
    F1LZM0
    Related
    ENSRNOP00000058404.3, ENSRNOT00000061693.6

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    11772180..11818751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006239738.4 → XP_006239800.1  forkhead box protein N2 isoform X1

    See identical proteins and their annotated locations for XP_006239800.1

    UniProtKB/TrEMBL
    F1LZM0
    Conserved Domains (1) summary
    cd20058
    Location:111 → 192
    FH_FOXN2; Forkhead (FH) domain found in Forkhead box protein N2 (FOXN2)

  2. XM_237502.10 → XP_237502.5  forkhead box protein N2 isoform X1

    See identical proteins and their annotated locations for XP_237502.5

    UniProtKB/TrEMBL
    F1LZM0
    Conserved Domains (1) summary
    cd20058
    Location:111 → 192
    FH_FOXN2; Forkhead (FH) domain found in Forkhead box protein N2 (FOXN2)

  3. XM_039113053.2 → XP_038968981.1  forkhead box protein N2 isoform X1

    UniProtKB/TrEMBL
    F1LZM0
    Conserved Domains (1) summary
    cd20058
    Location:111 → 192
    FH_FOXN2; Forkhead (FH) domain found in Forkhead box protein N2 (FOXN2)

  4. XM_039113051.2 → XP_038968979.1  forkhead box protein N2 isoform X1

    UniProtKB/TrEMBL
    F1LZM0
    Conserved Domains (1) summary
    cd20058
    Location:111 → 192
    FH_FOXN2; Forkhead (FH) domain found in Forkhead box protein N2 (FOXN2)

  5. XM_039113052.2 → XP_038968980.1  forkhead box protein N2 isoform X1

    UniProtKB/TrEMBL
    F1LZM0
    Conserved Domains (1) summary
    cd20058
    Location:111 → 192
    FH_FOXN2; Forkhead (FH) domain found in Forkhead box protein N2 (FOXN2)
Nucleotide Protein Strain
Heading Accession and Version

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