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Scd3 stearoyl-coenzyme A desaturase 3 [ Mus musculus (house mouse) ]

Gene ID: 30049, updated on 22-Nov-2020

Summary

Official Symbol
Scd3provided by MGI
Official Full Name
stearoyl-coenzyme A desaturase 3provided by MGI
Primary source
MGI:MGI:1353437
See related
Ensembl:ENSMUSG00000025202
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4930513N16Rik
Expression
Biased expression in subcutaneous fat pad adult (RPKM 90.3), mammary gland adult (RPKM 75.0) and 6 other tissues See more

Genomic context

See Scd3 in Genome Data Viewer
Location:
19; 19 C3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (44191727..44232455)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (44203288..44244016)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (44277778..44318506)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene CWF19-like 1, cell cycle control (S. pombe) Neighboring gene predicted gene, 52383 Neighboring gene biogenesis of lysosomal organelles complex-1, subunit 2 Neighboring gene polycystic kidney disease 2-like 1 Neighboring gene stearoyl-coenzyme A desaturase pseudogene Neighboring gene uncharacterized LOC118568395 Neighboring gene predicted gene, 35183

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (3)  1 citation
  • Endonuclease-mediated (1) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
iron ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water IEA
Inferred from Electronic Annotation
more info
 
palmitoyl-CoA 9-desaturase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
palmitoyl-CoA 9-desaturase activity IDA
Inferred from Direct Assay
more info
PubMed 
palmitoyl-CoA 9-desaturase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
NOT stearoyl-CoA 9-desaturase activity IDA
Inferred from Direct Assay
more info
PubMed 
NOT stearoyl-CoA 9-desaturase activity IGI
Inferred from Genetic Interaction
more info
PubMed 
Process Evidence Code Pubs
fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
monounsaturated fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
monounsaturated fatty acid biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
monounsaturated fatty acid biosynthetic process IGI
Inferred from Genetic Interaction
more info
PubMed 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
response to fatty acid IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
unsaturated fatty acid biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
acyl-CoA desaturase 3
Names
delta(9)-desaturase 3
fatty acid desaturase 3
palmitoyl-CoA desaturase
stearoyl-CoA desaturase 3

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024450.2NP_077770.1  acyl-CoA desaturase 3

    See identical proteins and their annotated locations for NP_077770.1

    Status: VALIDATED

    Source sequence(s)
    AC123853, AC125101, AF272037
    Consensus CDS
    CCDS29847.1
    UniProtKB/Swiss-Prot
    Q99PL7
    Related
    ENSMUSP00000026220.5, ENSMUST00000026220.6
    Conserved Domains (2) summary
    cd03505
    Location:97337
    Delta9-FADS-like; The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide ...
    pfam00487
    Location:102306
    FA_desaturase; Fatty acid desaturase

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000085.7 Reference GRCm39 C57BL/6J

    Range
    44191727..44232455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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