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FOL2 GTP cyclohydrolase I [ Sugiyamaella lignohabitans ]

Gene ID: 30036966, updated on 9-Jan-2024

Summary

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Gene symbol
FOL2
Gene description
GTP cyclohydrolase I
Locus tag
AWJ20_4796
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sugiyamaella lignohabitans (strain: CBS 10342, type-material: culture from holotype of Candida lignohabitans)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Trichomonascaceae; Sugiyamaella
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Genomic context

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Location:
chromosome: D
Exon count:
1
Sequence:
Chromosome: D; NC_031673.1 (573354..574247, complement)

Chromosome D - NC_031673.1Genomic Context describing neighboring genes Neighboring gene TFIIH/NER complex subunit TFB3 Neighboring gene Rcr2p Neighboring gene Hua1p Neighboring gene tRNA-Thr

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_031673.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTP cyclohydrolase I activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrobiopterin biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GTP cyclohydrolase I
XP_018736325.1
  • GTP-cyclohydrolase I; catalyzes the first step in the folic acid biosynthetic pathway; GO_component: GO:0005737 - cytoplasm [Evidence IEA]; GO_component: GO:0005737 - cytoplasm [Evidence IDA] [PMID 11914276]; GO_component: GO:0005737 - cytoplasm [Evidence IDA] [PMID 14562095]; GO_component: GO:0005634 - nucleus [Evidence IDA] [PMID 14562095]; GO_function: GO:0005525 - GTP binding [Evidence IEA]; GO_function: GO:0003934 - GTP cyclohydrolase I activity [Evidence IEA,IEA]; GO_function: GO:0003934 - GTP cyclohydrolase I activity [Evidence IMP] [PMID 8573145]; GO_function: GO:0003824 - catalytic activity [Evidence IEA]; GO_function: GO:0016787 - hydrolase activity [Evidence IEA]; GO_function: GO:0046872 - metal ion binding [Evidence IEA]; GO_function: GO:0000166 - nucleotide binding [Evidence IEA]; GO_process: GO:0035998 - 7,8-dihydroneopterin 3'-triphosphate biosynthetic process [Evidence IEA]; GO_process: GO:0046656 - folic acid biosynthetic process [Evidence IEA]; GO_process: GO:0009396 - folic acid-containing compound biosynthetic process [Evidence IMP] [PMID 8573145]; GO_process: GO:0008152 - metabolic process [Evidence IEA]; GO_process: GO:0046654 - tetrahydrofolate biosynthetic process [Evidence IEA]

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_031673.1 Reference assembly

    Range
    573354..574247 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018881891.1 → XP_018736325.1  GTP cyclohydrolase I [Sugiyamaella lignohabitans]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A167EAT3
Nucleotide Protein
Heading Accession and Version

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