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SMC6 DNA repair protein SMC6 [ Sugiyamaella lignohabitans ]

Gene ID: 30035899, updated on 9-Jan-2024

Summary

Gene symbol
SMC6
Gene description
DNA repair protein SMC6
Locus tag
AWJ20_3834
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sugiyamaella lignohabitans (strain: CBS 10342, type-material: culture from holotype of Candida lignohabitans)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Trichomonascaceae; Sugiyamaella
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Genomic context

Location:
chromosome: C
Exon count:
1
Sequence:
Chromosome: C; NC_031671.1 (402676..403341)

Chromosome C - NC_031671.1Genomic Context describing neighboring genes Neighboring gene bifunctional K:H/Na:H antiporter NHX1 Neighboring gene DNA repair protein SMC6 Neighboring gene Uso1p Neighboring gene Uso1p

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of Smc5-Smc6 complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in site of double-strand break IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
DNA repair protein SMC6
XP_018733515.1
  • Component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; homologous to S. pombe rad18; GO_component: GO:0030915 - Smc5-Smc6 complex [Evidence IEA]; GO_component: GO:0030915 - Smc5-Smc6 complex [Evidence IDA] [PMID 15738391]; GO_component: GO:0005694 - chromosome [Evidence IEA,IEA]; GO_component: GO:0005739 - mitochondrion [Evidence IDA] [PMID 14576278]; GO_component: GO:0005739 - mitochondrion [Evidence IDA] [PMID 16823961]; GO_component: GO:0005634 - nucleus [Evidence IEA,IEA]; GO_component: GO:0005634 - nucleus [Evidence IDA] [PMID 11927594]; GO_component: GO:0035861 - site of double-strand break [Evidence IDA] [PMID 16892052]; GO_function: GO:0005524 - ATP binding [Evidence IEA]; GO_function: GO:0019789 - SUMO ligase activity [Evidence IDA] [PMID 15738391]; GO_function: GO:0003684 - damaged DNA binding [Evidence IDA] [PMID 16793545]; GO_function: GO:0000166 - nucleotide binding [Evidence IEA]; GO_process: GO:0006310 - DNA recombination [Evidence IEA]; GO_process: GO:0006281 - DNA repair [Evidence IEA,IEA]; GO_process: GO:0006281 - DNA repair [Evidence IDA] [PMID 11927594]; GO_process: GO:0006281 - DNA repair [Evidence IMP] [PMID 15738391]; GO_process: GO:0006974 - cellular response to DNA damage stimulus [Evidence IEA]; GO_process: GO:0051304 - chromosome separation [Evidence IMP] [PMID 15793567]; GO_process: GO:0000724 - double-strand break repair via homologous recombination [Evidence IEA]; GO_process: GO:0000724 - double-strand break repair via homologous recombination [Evidence IMP] [PMID 16892052]; GO_process: GO:0071139 - resolution of recombination intermediates [Evidence IMP] [PMID 20159973]

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_031671.1 Reference assembly

    Range
    402676..403341
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018880867.1XP_018733515.1  DNA repair protein SMC6 [Sugiyamaella lignohabitans]

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A161HIM4