Lypd2 Ly6/Plaur domain containing 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Lypd2provided by RGD
Official Full Name: Ly6/Plaur domain containing 2provided by RGD
Primary source: RGD:1307892
See related: Ensembl:ENSRNOG00000006058 AllianceGenome:RGD:1307892
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be located in plasma membrane and side of membrane. Orthologous to human LYPD2 (LY6/PLAUR domain containing 2). [provided by Alliance of Genome Resources, Apr 2025]
Expression: Biased expression in Lung (RPKM 28.3) and Kidney (RPKM 7.2) See more
Orthologs: human mouse all
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Genomic context

Location:: 7q34

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	7	NC_086025.1 (108506545..108508582, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	7	NC_051342.1 (106617561..106619598, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	7	NC_005106.4 (115967267..115969304, complement)

Chromosome 7 - NC_086025.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Component	Evidence Code	Pubs
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: ly6/PLAUR domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001130545.1 → NP_001124017.2 ly6/PLAUR domain-containing protein 2 precursor

See identical proteins and their annotated locations for NP_001124017.2

Status: VALIDATED

Source sequence(s)

CB716336, JAXUCZ010000007

UniProtKB/TrEMBL

A6HRX8, A6HRX9, D4A707

Related

ENSRNOP00000007958.6, ENSRNOT00000007958.8

Conserved Domains (1) summary

cd00117
Location:23 → 102

LU; Ly-6 antigen / uPA receptor -like domain; occurs singly in GPI-linked cell-surface glycoproteins (Ly-6 family,CD59, thymocyte B cell antigen, Sgp-2) or as three-fold repeated domain in urokinase-type plasminogen activator receptor. Topology of these ...