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BICRA BRD4 interacting chromatin remodeling complex associated protein [ Homo sapiens (human) ]

Gene ID: 29998, updated on 15-Jun-2019

Summary

Official Symbol
BICRAprovided by HGNC
Official Full Name
BRD4 interacting chromatin remodeling complex associated proteinprovided by HGNC
Primary source
HGNC:HGNC:4332
See related
Ensembl:ENSG00000063169 MIM:605690
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GLTSCR1
Expression
Ubiquitous expression in spleen (RPKM 1.9), prostate (RPKM 1.7) and 25 other tissues See more
Orthologs

Genomic context

See BICRA in Genome Data Viewer
Location:
19q13.33
Exon count:
17
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 19 NC_000019.10 (47608196..47703277)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (48111453..48206534)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene zinc finger protein 541 Neighboring gene RNA, 7SL, cytoplasmic 322, pseudogene Neighboring gene EH domain containing 2 Neighboring gene NOP53 ribosome biogenesis factor Neighboring gene small nucleolar RNA, C/D box 23

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
transcription coactivator activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
positive regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
SWI/SNF complex IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IMP
Inferred from Mutant Phenotype
more info
PubMed 

General protein information

Preferred Names
BRD4-interacting chromatin-remodeling complex-associated protein
Names
BRD4 interacting chromatin remodelling complex associated protein
glioma tumor suppressor candidate region gene 1 protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015711.3NP_056526.3  BRD4-interacting chromatin-remodeling complex-associated protein

    See identical proteins and their annotated locations for NP_056526.3

    Status: VALIDATED

    Source sequence(s)
    AA961479, AA994408, AF182077, BC032065, BX362862
    Consensus CDS
    CCDS46134.1
    UniProtKB/Swiss-Prot
    Q9NZM4
    Related
    ENSP00000379946.2, ENST00000396720.7
    Conserved Domains (1) summary
    pfam15249
    Location:10881192
    GLTSCR1; Conserved region of unknown function on GLTSCR protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    47608196..47703277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005258833.4XP_005258890.1  BRD4-interacting chromatin-remodeling complex-associated protein isoform X1

    See identical proteins and their annotated locations for XP_005258890.1

    UniProtKB/Swiss-Prot
    Q9NZM4
    Conserved Domains (1) summary
    pfam15249
    Location:10881192
    GLTSCR1; Conserved region of unknown function on GLTSCR protein
  2. XM_011526883.2XP_011525185.1  BRD4-interacting chromatin-remodeling complex-associated protein isoform X3

    Conserved Domains (1) summary
    pfam15249
    Location:10291133
    GLTSCR1; Conserved region of unknown function on GLTSCR protein
  3. XM_006723180.3XP_006723243.1  BRD4-interacting chromatin-remodeling complex-associated protein isoform X4

    Conserved Domains (1) summary
    pfam15249
    Location:728832
    GLTSCR1; Conserved region of unknown function on GLTSCR protein
  4. XM_011526882.2XP_011525184.1  BRD4-interacting chromatin-remodeling complex-associated protein isoform X2

    Related
    ENSP00000480219.1, ENST00000614245.1
    Conserved Domains (1) summary
    pfam15249
    Location:10421146
    GLTSCR1; Conserved region of unknown function on GLTSCR protein
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