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Gsdmc gasdermin C [ Rattus norvegicus (Norway rat) ]

Gene ID: 299908, updated on 18-Apr-2019

Summary

Official Symbol
Gsdmcprovided by RGD
Official Full Name
gasdermin Cprovided by RGD
Primary source
RGD:1308989
See related
Ensembl:ENSRNOG00000054576
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mlze; Gsdmc1
Expression
Biased expression in Lung (RPKM 5.6), Thymus (RPKM 4.9) and 6 other tissues See more
Orthologs

Genomic context

See Gsdmc in Genome Data Viewer
Location:
7q33
Exon count:
13
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (104474418..104492373, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (91477763..91495324, complement)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102548624 Neighboring gene similar to isocitrate dehydrogenase 3 (NAD+) beta Neighboring gene gasdermin domain containing protein RGD1359449 Neighboring gene uncharacterized LOC103692930 Neighboring gene family with sequence similarity 49, member B

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
phosphatidylinositol-4,5-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol-4-phosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylserine binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
pyroptosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol IEA
Inferred from Electronic Annotation
more info
 
microtubule organizing center ISO
Inferred from Sequence Orthology
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
gasdermin-C
Names
gasdermin C1
melanoma-derived leucine zipper, extra-nuclear factor
melanoma-derived leucine zipper-containing extranuclear factor

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001134495.1NP_001127967.1  gasdermin-C

    Status: PROVISIONAL

    Source sequence(s)
    AABR07058199
    UniProtKB/TrEMBL
    D3ZJF3
    Related
    ENSRNOP00000072537.1, ENSRNOT00000084764.1
    Conserved Domains (1) summary
    pfam04598
    Location:4441
    Gasdermin; Gasdermin family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

    Range
    104474418..104492373 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017594749.1XP_017450238.1  gasdermin-C isoform X1

    UniProtKB/TrEMBL
    D3ZJF3
    Conserved Domains (1) summary
    pfam04598
    Location:4441
    Gasdermin; Gasdermin family

Alternate Rn_Celera

Genomic

  1. AC_000075.1 Alternate Rn_Celera

    Range
    92191820..92203910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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