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CDIP1 cell death inducing p53 target 1 [ Homo sapiens (human) ]

Gene ID: 29965, updated on 5-Aug-2018

Summary

Official Symbol
CDIP1provided by HGNC
Official Full Name
cell death inducing p53 target 1provided by HGNC
Primary source
HGNC:HGNC:13234
See related
Ensembl:ENSG00000089486 MIM:610503; Vega:OTTHUMG00000177172
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
I1; CDIP; LITAFL; C16orf5
Expression
Ubiquitous expression in brain (RPKM 37.0), kidney (RPKM 18.1) and 24 other tissues See more
Orthologs

Genomic context

See CDIP1 in Genome Data Viewer
Location:
16p13.3
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 16 NC_000016.10 (4510675..4538815, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (4560676..4588816, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member A3 Neighboring gene NmrA like redox sensor 1 Neighboring gene heme oxygenase 2 Neighboring gene chromosome 16 open reading frame 96 Neighboring gene SUB1 homolog, transcriptional regulator pseudogene 3 Neighboring gene UBA like domain containing 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apoptotic process IGI
Inferred from Genetic Interaction
more info
PubMed 
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
Inferred from Mutant Phenotype
more info
PubMed 
tumor necrosis factor-mediated signaling pathway IGI
Inferred from Genetic Interaction
more info
PubMed 
Component Evidence Code Pubs
cytoplasmic side of late endosome membrane IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasmic side of lysosomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
cell death-inducing p53-target protein 1
Names
LITAF-like protein
cell death inducing protein
cell death involved p53-target
lipopolysaccharide-induced tumor necrosis factor-alpha-like protein
transmembrane protein I1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001199054.1NP_001185983.1  cell death-inducing p53-target protein 1 isoform a

    See identical proteins and their annotated locations for NP_001185983.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC007606, AL833853
    Consensus CDS
    CCDS42114.1
    UniProtKB/Swiss-Prot
    Q9H305
    Related
    ENSP00000454994.1, OTTHUMP00000256026, ENST00000563332.6, OTTHUMT00000435717
    Conserved Domains (1) summary
    pfam10601
    Location:137203
    zf-LITAF-like; LITAF-like zinc ribbon domain
  2. NM_001199055.1NP_001185984.1  cell death-inducing p53-target protein 1 isoform b

    See identical proteins and their annotated locations for NP_001185984.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AC007606, AK294257, AK308532
    Consensus CDS
    CCDS58419.1
    UniProtKB/Swiss-Prot
    Q9H305
    Related
    ENSP00000455462.1, OTTHUMP00000256031, ENST00000563507.5, OTTHUMT00000435722
    Conserved Domains (1) summary
    pfam10601
    Location:98166
    zf-LITAF-like; LITAF-like zinc ribbon domain
  3. NM_001199056.1NP_001185985.1  cell death-inducing p53-target protein 1 isoform c

    See identical proteins and their annotated locations for NP_001185985.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and lacks an alternate internal segemnt compared to variant 1. The resulting isoform (c) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AC007606, AK302297, AK308532
    Consensus CDS
    CCDS58420.1
    UniProtKB/Swiss-Prot
    Q9H305
    Related
    ENSP00000455050.1, OTTHUMP00000256032, ENST00000562334.5, OTTHUMT00000435723
    Conserved Domains (1) summary
    pfam10601
    Location:58126
    zf-LITAF-like; LITAF-like zinc ribbon domain
  4. NM_013399.2NP_037531.2  cell death-inducing p53-target protein 1 isoform a

    See identical proteins and their annotated locations for NP_037531.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AC007606, BC002882, DA055704
    Consensus CDS
    CCDS42114.1
    UniProtKB/Swiss-Prot
    Q9H305
    Related
    ENSP00000457877.1, OTTHUMP00000256028, ENST00000567695.5, OTTHUMT00000435719
    Conserved Domains (1) summary
    pfam10601
    Location:137203
    zf-LITAF-like; LITAF-like zinc ribbon domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p12 Primary Assembly

    Range
    4510675..4538815 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p12 ALT_REF_LOCI_1

Genomic

  1. NT_187608.1 Reference GRCh38.p12 ALT_REF_LOCI_1

    Range
    212998..216989 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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