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Uxt ubiquitously-expressed, prefoldin-like chaperone [ Rattus norvegicus (Norway rat) ]

Gene ID: 299313, updated on 2-Oct-2018

Summary

Official Symbol
Uxtprovided by RGD
Official Full Name
ubiquitously-expressed, prefoldin-like chaperoneprovided by RGD
Primary source
RGD:1359326
See related
Ensembl:ENSRNOG00000009893
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Heart (RPKM 234.2), Kidney (RPKM 226.9) and 9 other tissues See more
Orthologs

Genomic context

See Uxt in Genome Data Viewer
Location:
Xq11
Exon count:
7
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (1275402..1287781)
104 previous assembly Rnor_5.0 (GCF_000001895.4) X NC_005120.3 (2090439..2102802)

Chromosome X - NC_005120.4Genomic Context describing neighboring genes Neighboring gene zinc finger protein 300 Neighboring gene zinc finger protein 182 Neighboring gene sperm acrosome associated 5 Neighboring gene zinc finger protein 81 (HFZ20)-like Neighboring gene ELK1, ETS transcription factor Neighboring gene complement factor properdin

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Clone Names

  • MGC105797

Gene Ontology Provided by RGD

Function Evidence Code Pubs
NOT actin filament binding ISO
Inferred from Sequence Orthology
more info
 
beta-tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
beta-tubulin binding ISO
Inferred from Sequence Orthology
more info
 
beta-tubulin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
chromatin binding ISO
Inferred from Sequence Orthology
more info
 
chromatin binding ISS
Inferred from Sequence or Structural Similarity
more info
 
transcription corepressor activity ISO
Inferred from Sequence Orthology
more info
 
transcription corepressor activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
centrosome cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centrosome cycle ISO
Inferred from Sequence Orthology
more info
 
centrosome cycle ISS
Inferred from Sequence or Structural Similarity
more info
 
microtubule cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
microtubule cytoskeleton organization ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
centrosome ISO
Inferred from Sequence Orthology
more info
 
centrosome ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton ISS
Inferred from Sequence or Structural Similarity
more info
 
colocalizes_with gamma-tubulin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with gamma-tubulin complex ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with gamma-tubulin complex ISS
Inferred from Sequence or Structural Similarity
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
spindle pole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein UXT
Names
ubiquitously expressed transcript protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001006982.1NP_001006983.1  protein UXT

    See identical proteins and their annotated locations for NP_001006983.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082752
    UniProtKB/Swiss-Prot
    Q63ZY7
    Related
    ENSRNOP00000013476.4, ENSRNOT00000013476.7
    Conserved Domains (1) summary
    cd00584
    Location:18147
    Prefoldin_alpha; Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005120.4 Reference Rnor_6.0 Primary Assembly

    Range
    1275402..1287781
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006256611.3XP_006256673.1  protein UXT isoform X1

    See identical proteins and their annotated locations for XP_006256673.1

    UniProtKB/Swiss-Prot
    Q63ZY7
    Conserved Domains (1) summary
    cd00584
    Location:18147
    Prefoldin_alpha; Prefoldin alpha subunit; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta ...

Alternate Rn_Celera

Genomic

  1. AC_000089.1 Alternate Rn_Celera

    Range
    1695268..1707300
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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