Format

Send to:

Choose Destination

LINC00312 long intergenic non-protein coding RNA 312 [ Homo sapiens (human) ]

Gene ID: 29931, updated on 12-Oct-2019

Summary

Official Symbol
LINC00312provided by HGNC
Official Full Name
long intergenic non-protein coding RNA 312provided by HGNC
Primary source
HGNC:HGNC:6662
See related
MIM:610485
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NAG7; ERR10; NAG-7; ERR-10; LMCD1DN; LOH3CR2A; NCRNA00312
Summary
This gene produces an intronless transcript that is thought to function as a tumor suppressor. This transcript is downregulated in nasopharyngeal carcinoma and is a negative regulator of estrogen receptor signaling. A common polymorphism in this transcript allows the production of a 94 aa open reading frame in some individuals, which may interact directly with estrogen receptor 1 (PMID:15474036). This open reading frame does not exist on the reference genome haplotype, which is hypothesized to function through a non-coding RNA product. [provided by RefSeq, Mar 2017]

Genomic context

See LINC00312 in Genome Data Viewer
Location:
3p25.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (8571782..8574668)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (8613468..8616354)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101927394 Neighboring gene LMCD1 antisense RNA 1 Neighboring gene uncharacterized LOC107986010 Neighboring gene RNA, U4atac small nuclear 17, pseudogene Neighboring gene uncharacterized LOC107986009 Neighboring gene LIM and cysteine rich domains 1 Neighboring gene ssu-2 homolog Neighboring gene olfactory receptor family 7 subfamily E member 122 pseudogene Neighboring gene caveolin 3

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • LMCD1 downstream neighbor
  • estrogen receptor repressor 10
  • loss of heterozygosity, 3, chromosomal region 2, gene A
  • nasopharyngeal carcinoma candidate 7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_024065.3 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC087859

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    8571782..8574668
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_013343.1: Suppressed sequence

    Description
    NM_013343.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.
Support Center