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Erg28 ergosterol biosynthesis 28 homolog [ Rattus norvegicus (Norway rat) ]

Gene ID: 299207, updated on 5-Mar-2024

Summary

Official Symbol
Erg28provided by RGD
Official Full Name
ergosterol biosynthesis 28 homologprovided by RGD
Primary source
RGD:1310769
See related
Ensembl:ENSRNOG00000008781 AllianceGenome:RGD:1310769
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1310769
Summary
Predicted to enable identical protein binding activity and protein-macromolecule adaptor activity. Predicted to be involved in lipid metabolic process. Predicted to be located in transport vesicle. Predicted to be active in endoplasmic reticulum. Orthologous to human ERG28 (ergosterol biosynthesis 28 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in Liver (RPKM 308.7), Lung (RPKM 109.4) and 9 other tissues See more
Orthologs
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Genomic context

Location:
6q31
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (111205102..111214068, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (105474112..105483078, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (109683252..109692218, complement)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108351275 Neighboring gene basic leucine zipper ATF-like transcription factor Neighboring gene uncharacterized LOC120103579 Neighboring gene FLVCR choline and putative heme transporter 2 Neighboring gene tubulin tyrosine ligase like 5 Neighboring gene uncharacterized LOC134479235 Neighboring gene transforming growth factor, beta 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables protein-macromolecule adaptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
located_in transport vesicle IEA
Inferred from Electronic Annotation
more info
 
located_in transport vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ergosterol biosynthetic protein 28 homolog
Names
probable ergosterol biosynthetic protein 28

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106749.1NP_001100219.1  ergosterol biosynthetic protein 28 homolog

    See identical proteins and their annotated locations for NP_001100219.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473982
    UniProtKB/TrEMBL
    A6JE40, D3ZBN4
    Related
    ENSRNOP00000012327.4, ENSRNOT00000012327.6
    Conserved Domains (1) summary
    pfam03694
    Location:8115
    Erg28; Erg28 like protein

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    111205102..111214068 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063261754.1XP_063117824.1  ergosterol biosynthetic protein 28 homolog isoform X1