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Actr10 actin related protein 10 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299121, updated on 5-Sep-2025
Official Symbol
Actr10provided by RGD
Official Full Name
actin related protein 10provided by RGD
Primary source
RGD:1306515
See related
Ensembl:ENSRNOG00000007504 AllianceGenome:RGD:1306515
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
Predicted to be involved in retrograde axonal transport of mitochondrion. Predicted to act upstream of or within microtubule-based movement. Predicted to be located in axon cytoplasm. Predicted to be part of dynactin complex. Orthologous to human ACTR10 (actin related protein 10). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Biased expression in Testes (RPKM 840.9), Muscle (RPKM 377.1) and 9 other tissues See more
Orthologs
human mouse all
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See Actr10 in Genome Data Viewer
Location:
6q24
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 6 NC_086024.1 (95182082..95208325)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 6 NC_051341.1 (89446141..89472350)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 6 NC_005105.4 (93385457..93411605)

Chromosome 6 - NC_086024.1Genomic Context describing neighboring genes Neighboring gene FERM domain containing 6 Neighboring gene small nucleolar RNA, C/D box 45 like 1 Neighboring gene transfer RNA alanine (anticodon AGC) 24 Neighboring gene transfer RNA lysine (anticodon CUU) 9 Neighboring gene proteasome 20S subunit alpha 3

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Dynactin. Schroer TA. Annu Rev Cell Dev Biol, 2004. PMID 15473859
  2. Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end. Eckley DM, et al. J Cell Biol, 1999 Oct 18. PMID 10525537, Free PMC Article
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Clone Names

  • MGC95127

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
acts_upstream_of_or_within microtubule-based movement ISO
Inferred from Sequence Orthology
more info
  
involved_in retrograde axonal transport of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in axon cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
part_of dynactin complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of dynactin complex ISO
Inferred from Sequence Orthology
more info
  
Preferred Names
actin-related protein 10
Names
actin-related protein 10 homolog

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001009602.1 → NP_001009602.1  actin-related protein 10

    See identical proteins and their annotated locations for NP_001009602.1

    Status: PROVISIONAL

    Source sequence(s)
    BC087143
    UniProtKB/TrEMBL
    F7F7Z6, Q5M9F7
    Related
    ENSRNOP00000085016.2, ENSRNOT00000103813.2
    Conserved Domains (1) summary
    cl17037
    Location:13 → 364
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086024.1 Reference GRCr8

    Range
    95182082..95208325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039111995.2 → XP_038967923.1  actin-related protein 10 isoform X1

    Conserved Domains (1) summary
    cl17037
    Location:13 → 181
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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