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SAC3D1 SAC3 domain containing 1 [ Homo sapiens (human) ]

Gene ID: 29901, updated on 1-Jun-2020

Summary

Official Symbol
SAC3D1provided by HGNC
Official Full Name
SAC3 domain containing 1provided by HGNC
Primary source
HGNC:HGNC:30179
See related
Ensembl:ENSG00000168061 MIM:618796
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
SHD1; HSU79266
Expression
Broad expression in testis (RPKM 7.3), colon (RPKM 3.1) and 23 other tissues See more
Orthologs

Genomic context

See SAC3D1 in Genome Data Viewer
Location:
11q13.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (65040933..65044828)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (64808376..64812300)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene ARL2-SNX15 readthrough (NMD candidate) Neighboring gene Sharpr-MPRA regulatory region 4003 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 18 Neighboring gene sorting nexin 15 Neighboring gene N-acetylated alpha-linked acidic dipeptidase like 1 Neighboring gene cell division cycle associated 5 Neighboring gene zinc finger protein like 1 Neighboring gene transmembrane protein 262

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
cell division IEA
Inferred from Electronic Annotation
more info
 
centrosome duplication IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
spindle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
SAC3 domain-containing protein 1
Names
SAC3 homology domain-containing protein 1
Sac3 homology domain 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001367485.1NP_001354414.1  SAC3 domain-containing protein 1 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2), as well as variant 1, encodes isoform a.
    Source sequence(s)
    AP003068
    Related
    ENSP00000436649.1, ENST00000531072.1
  2. NM_001367486.1NP_001354415.1  SAC3 domain-containing protein 1 isoform b

    Status: VALIDATED

    Source sequence(s)
    AP003068, U79266
    Related
    ENSP00000381824.2, ENST00000398846.6
  3. NM_001367487.1NP_001354416.1  SAC3 domain-containing protein 1 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4), as well as variant 5, encodes isoform c.
    Source sequence(s)
    AP003068
  4. NM_001367488.1NP_001354417.1  SAC3 domain-containing protein 1 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variant 4, encodes isoform c.
    Source sequence(s)
    AP003068
    Related
    ENSP00000501403.1, ENST00000674184.1
  5. NM_013299.4NP_037431.3  SAC3 domain-containing protein 1 isoform a

    See identical proteins and their annotated locations for NP_037431.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 2 both encode the same isoform (a).
    Source sequence(s)
    AP003068, BC007448
    Consensus CDS
    CCDS41668.1
    UniProtKB/TrEMBL
    F8WC89
    Related
    ENSP00000499090.1, ENST00000652489.1
    Conserved Domains (1) summary
    pfam03399
    Location:9302
    SAC3_GANP; SAC3/GANP family

RNA

  1. NR_160028.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP003068, BI088075
    Related
    ENST00000533017.1
  2. NR_160029.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AP003068

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    65040933..65044828
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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