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Rnf11 ring finger protein 11 [ Mus musculus (house mouse) ]

Gene ID: 29864, updated on 8-Feb-2024

Summary

Official Symbol
Rnf11provided by MGI
Official Full Name
ring finger protein 11provided by MGI
Primary source
MGI:MGI:1352759
See related
Ensembl:ENSMUSG00000028557 AllianceGenome:MGI:1352759
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable ubiquitin protein ligase activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Part of ubiquitin ligase complex. Is expressed in several structures, including cardiovascular system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human RNF11 (ring finger protein 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 155.5), ovary adult (RPKM 53.5) and 28 other tissues See more
Orthologs
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Genomic context

See Rnf11 in Genome Data Viewer
Location:
4 C7; 4 51.29 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (109310054..109333702, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (109452857..109476505, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene epidermal growth factor receptor pathway substrate 15 Neighboring gene basic leucine zipper and W2 domains 1 pseudogene Neighboring gene Ttc39a opposite strand RNA 1 Neighboring gene tetratricopeptide repeat domain 39A Neighboring gene STARR-seq mESC enhancer starr_11070 Neighboring gene RIKEN cDNA 4930522H14 gene Neighboring gene STARR-positive B cell enhancer ABC_E4645 Neighboring gene predicted gene, 22497

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables ubiquitin protein ligase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in protein autoubiquitination ISO
Inferred from Sequence Orthology
more info
 
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process IPI
Inferred from Physical Interaction
more info
PubMed 
involved_in ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of ubiquitin ligase complex IPI
Inferred from Physical Interaction
more info
PubMed 
part_of ubiquitin ligase complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
RING finger protein 11
Names
NEDD4 WW domain-binding protein 2
sid 1669

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013876.3NP_038904.1  RING finger protein 11

    See identical proteins and their annotated locations for NP_038904.1

    Status: PROVISIONAL

    Source sequence(s)
    AL669905
    Consensus CDS
    CCDS18464.1
    UniProtKB/Swiss-Prot
    B1AU36, B1AU37, Q9EQI1, Q9QYK7
    UniProtKB/TrEMBL
    Z4YLT8
    Related
    ENSMUSP00000030284.4, ENSMUST00000030284.10
    Conserved Domains (1) summary
    cd16468
    Location:98140
    RING-H2_RNF11; RING finger, H2 subclass, found in RING finger protein 11 (RNF11) and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    109310054..109333702 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)