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Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 297554, updated on 5-Jul-2025
Official Symbol
Csgalnact2provided by RGD
Official Full Name
chondroitin sulfate N-acetylgalactosaminyltransferase 2provided by RGD
Primary source
RGD:1563660
See related
Ensembl:ENSRNOG00000014713 AllianceGenome:RGD:1563660
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Galnact2; RGD1563660
Summary
Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Predicted to be involved in chondroitin sulfate proteoglycan biosynthetic process and dermatan sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi cisterna membrane. Predicted to be active in Golgi apparatus. Orthologous to human CSGALNACT2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Lung (RPKM 242.4), Muscle (RPKM 183.0) and 9 other tissues See more
Orthologs
human mouse all
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See Csgalnact2 in Genome Data Viewer
Location:
4q42
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (152944154..152981237, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (151271774..151308856, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (150148626..150185062, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120102376 Neighboring gene uncharacterized LOC134486839 Neighboring gene RasGEF domain family, member 1A Neighboring gene small nucleolar RNA SNORA17 Neighboring gene developmental pluripotency-associated 3, pseudogene 3 Neighboring gene ret proto-oncogene

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate. Uyama T, et al. J Biol Chem, 2002 Mar 15. PMID 11788602
  2. Chondroitin 4-O-sulfotransferase-1 regulates the chain length of chondroitin sulfate in co-operation with chondroitin N-acetylgalactosaminyltransferase-2. Izumikawa T, et al. Biochem J, 2011 Mar 1. PMID 21138417
  3. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables acetylgalactosaminyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity ISO
Inferred from Sequence Orthology
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chondroitin sulfate proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in chondroitin sulfate proteoglycan biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chondroitin sulfate proteoglycan biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in chondroitin sulfate proteoglycan biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in dermatan sulfate proteoglycan biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in dermatan sulfate proteoglycan biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
involved_in proteoglycan biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
involved_in proteoglycan biosynthetic process ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
chondroitin sulfate N-acetylgalactosaminyltransferase 2
Names
chondroitin sulfate GalNAcT-2
NP_001100086.1
XP_006237243.1
XP_006237244.1
XP_017448072.1
XP_017448073.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106616.1 → NP_001100086.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2

    See identical proteins and their annotated locations for NP_001100086.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473964
    UniProtKB/TrEMBL
    A6IL55, D4A5Z0
    Related
    ENSRNOP00000019778.4, ENSRNOT00000019778.6
    Conserved Domains (1) summary
    cl11394
    Location:67 → 516
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    152944154..152981237 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017592584.3 → XP_017448073.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X2

  2. XM_006237181.4 → XP_006237243.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X3

    Conserved Domains (1) summary
    cl11394
    Location:166 → 436
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  3. XM_017592583.3 → XP_017448072.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X1

    UniProtKB/TrEMBL
    A6IL55, D4A5Z0
    Conserved Domains (1) summary
    cl11394
    Location:67 → 516
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

  4. XM_006237182.5 → XP_006237244.1  chondroitin sulfate N-acetylgalactosaminyltransferase 2 isoform X4

    Conserved Domains (1) summary
    cl11394
    Location:67 → 445
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
Nucleotide Protein Strain
Heading Accession and Version

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