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Ctnna2 catenin alpha 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 297357, updated on 4-Feb-2021

Summary

Official Symbol
Ctnna2provided by RGD
Official Full Name
catenin alpha 2provided by RGD
Primary source
RGD:1305060
See related
Ensembl:ENSRNOG00000006003
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Catna2
Expression
Biased expression in Brain (RPKM 205.3) and Testes (RPKM 103.8) See more
Orthologs
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Genomic context

See Ctnna2 in Genome Data Viewer
Location:
4q33
Exon count:
21
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (109293978..110443413, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (107880611..109042724, complement)

Chromosome 4 - NC_051339.1Genomic Context describing neighboring genes Neighboring gene similar to ribosomal protein L6 Neighboring gene U6 spliceosomal RNA Neighboring gene leucine rich repeat transmembrane neuronal 1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene U11 spliceosomal RNA

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
actin filament binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament binding ISO
Inferred from Sequence Orthology
more info
 
beta-catenin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cadherin binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
axonogenesis ISO
Inferred from Sequence Orthology
more info
 
brain morphogenesis ISO
Inferred from Sequence Orthology
more info
 
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell-cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite morphogenesis ISO
Inferred from Sequence Orthology
more info
 
modification of postsynaptic actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
negative regulation of Arp2/3 complex-mediated actin nucleation ISO
Inferred from Sequence Orthology
more info
 
prepulse inhibition ISO
Inferred from Sequence Orthology
more info
 
radial glia guided migration of Purkinje cell ISO
Inferred from Sequence Orthology
more info
 
regulation of neuron migration ISO
Inferred from Sequence Orthology
more info
 
regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
regulation of synapse structural plasticity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
adherens junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
adherens junction ISO
Inferred from Sequence Orthology
more info
 
axon ISO
Inferred from Sequence Orthology
more info
 
basolateral plasma membrane ISO
Inferred from Sequence Orthology
more info
 
catenin complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
extrinsic component of postsynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
extrinsic component of presynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
hippocampal mossy fiber to CA3 synapse ISO
Inferred from Sequence Orthology
more info
 
lamellipodium ISO
Inferred from Sequence Orthology
more info
 
parallel fiber to Purkinje cell synapse ISO
Inferred from Sequence Orthology
more info
 
postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
postsynaptic density, intracellular component ISO
Inferred from Sequence Orthology
more info
 
presynaptic active zone cytoplasmic component ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
catenin alpha-2
Names
catenin (cadherin associated protein), alpha 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106598.1NP_001100068.1  catenin alpha-2

    See identical proteins and their annotated locations for NP_001100068.1

    Status: PROVISIONAL

    Source sequence(s)
    CH473957
    Conserved Domains (1) summary
    pfam01044
    Location:81914
    Vinculin; Vinculin family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051339.1 Reference mRatBN7.2 Primary Assembly

    Range
    109293978..110443413 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017592544.2XP_017448033.1  catenin alpha-2 isoform X1

  2. XM_017592546.2XP_017448035.1  catenin alpha-2 isoform X3

    Conserved Domains (1) summary
    pfam01044
    Location:94879
    Vinculin; Vinculin family
  3. XM_017592545.2XP_017448034.1  catenin alpha-2 isoform X2

    Conserved Domains (1) summary
    pfam01044
    Location:81914
    Vinculin; Vinculin family
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