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Chpf2 chondroitin polymerizing factor 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 296733, updated on 5-Jul-2025
Official Symbol
Chpf2provided by RGD
Official Full Name
chondroitin polymerizing factor 2provided by RGD
Primary source
RGD:1306404
See related
Ensembl:ENSRNOG00000010466 AllianceGenome:RGD:1306404
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1306404
Summary
Predicted to enable glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity. Predicted to be involved in chondroitin sulfate proteoglycan biosynthetic process. Predicted to be located in Golgi cisterna membrane. Predicted to be active in Golgi apparatus. Orthologous to human CHPF2 (chondroitin polymerizing factor 2). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Liver (RPKM 93.7), Brain (RPKM 91.4) and 9 other tissues See more
Orthologs
human mouse all
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See Chpf2 in Genome Data Viewer
Location:
4q11
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (11470917..11479096, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (10578470..10585940, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (7108461..7113940, complement)

Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134486541 Neighboring gene glycerol-3-phosphate dehydrogenase 1 like 3 Neighboring gene SWI/SNF related BAF chromatin remodeling complex subunit D3 Neighboring gene microRNA 671 Neighboring gene ATP binding cassette subfamily F member 2 Neighboring gene IQ motif containing with AAA domain 1 like

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in chondroitin sulfate proteoglycan biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
is_active_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
chondroitin sulfate glucuronyltransferase
NP_001100044.1
XP_008760855.1
XP_038963146.1
XP_063141763.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106574.1 → NP_001100044.1  chondroitin sulfate glucuronyltransferase precursor

    See identical proteins and their annotated locations for NP_001100044.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474020
    UniProtKB/TrEMBL
    A0A8I6AI88, A6K535, D4ADR5
    Related
    ENSRNOP00000014082.6, ENSRNOT00000014082.7
    Conserved Domains (2) summary
    pfam05679
    Location:242 → 757
    CHGN; Chondroitin N-acetylgalactosaminyltransferase
    cl21608
    Location:177 → 269
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086022.1 Reference GRCr8

    Range
    11470917..11479096 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039107218.2 → XP_038963146.1  chondroitin sulfate glucuronyltransferase isoform X1

    UniProtKB/TrEMBL
    A0A8I6AI88, A6K535, D4ADR5
    Conserved Domains (2) summary
    pfam05679
    Location:242 → 757
    CHGN; Chondroitin N-acetylgalactosaminyltransferase
    cl21608
    Location:177 → 269
    Galactosyl_T; Galactosyltransferase

  2. XM_008762633.3 → XP_008760855.1  chondroitin sulfate glucuronyltransferase isoform X1

    See identical proteins and their annotated locations for XP_008760855.1

    UniProtKB/TrEMBL
    A0A8I6AI88, A6K535, D4ADR5
    Conserved Domains (2) summary
    pfam05679
    Location:242 → 757
    CHGN; Chondroitin N-acetylgalactosaminyltransferase
    cl21608
    Location:177 → 269
    Galactosyl_T; Galactosyltransferase

  3. XM_063285693.1 → XP_063141763.1  chondroitin sulfate glucuronyltransferase isoform X2

RNA

  1. XR_010065615.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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