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UPA3_RS00610 dihydrofolate reductase [ Ureaplasma parvum serovar 3 str. ATCC 27815 ]

Gene ID: 29672261, updated on 3-Apr-2024

Summary

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Gene symbol
UPA3_RS00610
Gene description
dihydrofolate reductase
Locus tag
UPA3_RS00610
Gene type
protein coding
Organism
Ureaplasma parvum serovar 3 str. ATCC 27815 (strain: ATCC 27815, serovar: 3, type-material: type strain of Ureaplasma parvum)
Lineage
Bacteria; Mycoplasmatota; Mycoplasmoidales; Mycoplasmoidaceae; Ureaplasma
Old locus tag
UPA3_0119
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Genomic context

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Sequence:
NC_010503.1 (150399..150869)

NC_010503.1Genomic Context describing neighboring genes Neighboring gene 23S ribosomal RNA Neighboring gene 5S ribosomal RNA Neighboring gene HAD family hydrolase Neighboring gene tRNA-Gly

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_010503.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Dihydrofolate reductase: binding of substrates and inhibitors and catalytic mechanism. Gready JE. Adv Pharmacol Chemother, 1980. PMID 7004143

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
dihydrofolate reductase
WP_006689146.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_010503.1 Reference assembly

    Range
    150399..150869
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_006689146.1 dihydrofolate reductase [Ureaplasma parvum]

    See identical proteins and their annotated locations for WP_006689146.1

    UniProtKB/Swiss-Prot
    Q9PR30
    UniProtKB/TrEMBL
    A0A2C9DY38, A0AA86YC77
    Conserved Domains (1) summary
    cd00209
    Location:2 → 150
    DHFR; Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5, ...
Nucleotide Protein
Heading Accession and Version