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Psma2 proteasome subunit alpha 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29669, updated on 5-Aug-2018

Summary

Official Symbol
Psma2provided by RGD
Official Full Name
proteasome subunit alpha 2provided by RGD
Primary source
RGD:61842
See related
Ensembl:ENSRNOG00000049920
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
component of the proteasome multicatalytic proteinase complex [RGD, Feb 2006]
Expression
Biased expression in Adrenal (RPKM 833.1), Thymus (RPKM 825.0) and 9 other tissues See more
Orthologs

Genomic context

See Psma2 in Genome Data Viewer
Location:
17q12.1
Exon count:
8
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (53091937..53102324, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 17 NC_005116.3 (50791696..50802083, complement)

Chromosome 17 - NC_005116.4Genomic Context describing neighboring genes Neighboring gene heat shock protein 1, pseudogene 3 Neighboring gene similar to expressed sequence AW209491 Neighboring gene mitochondrial ribosomal protein L32 Neighboring gene HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 Neighboring gene histone-binding protein RBBP4-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
proteasomal protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasomal ubiquitin-independent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to virus ISO
Inferred from Sequence Orthology
more info
 
ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
P-body ISO
Inferred from Sequence Orthology
more info
 
P-body ISS
Inferred from Sequence or Structural Similarity
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
proteasome complex ISO
Inferred from Sequence Orthology
more info
 
proteasome core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome core complex ISO
Inferred from Sequence Orthology
more info
 
proteasome core complex ISS
Inferred from Sequence or Structural Similarity
more info
 
proteasome core complex, alpha-subunit complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome core complex, alpha-subunit complex ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
proteasome subunit alpha type-2
Names
macropain subunit C3
multicatalytic endopeptidase complex subunit C3
proteasome (prosome, macropain) subunit, alpha type 2
proteasome alpha 2 subunit
proteasome component C3
NP_058975.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017279.1NP_058975.1  proteasome subunit alpha type-2

    See identical proteins and their annotated locations for NP_058975.1

    Status: PROVISIONAL

    Source sequence(s)
    J02897
    UniProtKB/Swiss-Prot
    P17220
    Related
    ENSRNOP00000066950.1, ENSRNOT00000073834.2
    Conserved Domains (1) summary
    cd03750
    Location:6231
    proteasome_alpha_type_2; proteasome_alpha_type_2. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that stack on ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005116.4 Reference Rnor_6.0 Primary Assembly

    Range
    53091937..53102324 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000085.1 Alternate Rn_Celera

    Range
    46587061..46597448 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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