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Slc38a2 solute carrier family 38, member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29642, updated on 27-Nov-2020

Summary

Official Symbol
Slc38a2provided by RGD
Official Full Name
solute carrier family 38, member 2provided by RGD
Primary source
RGD:69420
See related
Ensembl:ENSRNOG00000006305
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ata2; Sat2; Atrc2; Snat2
Summary
alanine-preferring transporter; involved in nitrogen transport, alanine transport and acts as a substrate for oxidative metabolism [RGD, Feb 2006]
Expression
Biased expression in Heart (RPKM 579.0), Muscle (RPKM 513.1) and 9 other tissues See more
Orthologs

Genomic context

See Slc38a2 in Genome Data Viewer
Location:
7q35
Exon count:
15
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (138088654..138100869, complement)
106 current Rn_Celera (GCF_000002265.2) 7 AC_000075.1 (124355437..124367606, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 7 NC_005106.3 (137716131..137728346, complement)

Chromosome 7 - NC_005106.4Genomic Context describing neighboring genes Neighboring gene solute carrier family 38, member 1 Neighboring gene 40S ribosomal protein S13 pseudogene Neighboring gene uncharacterized LOC108351544 Neighboring gene uncharacterized LOC103692969

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
L-glutamine transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
L-glutamine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
L-glutamine transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
L-serine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
amino acid transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
amino acid transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
neutral amino acid:sodium symporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
L-serine transport IDA
Inferred from Direct Assay
more info
PubMed 
alanine transport IDA
Inferred from Direct Assay
more info
PubMed 
amino acid transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
amino acid transmembrane transport ISO
Inferred from Sequence Orthology
more info
 
amino acid transport ISO
Inferred from Sequence Orthology
more info
 
cellular response to amino acid starvation IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to arsenite(3-) ISO
Inferred from Sequence Orthology
more info
 
cellular response to mechanical stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cerebral cortex development IEP
Inferred from Expression Pattern
more info
PubMed 
female pregnancy IEP
Inferred from Expression Pattern
more info
PubMed 
glutamine transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
glutamine transport IDA
Inferred from Direct Assay
more info
PubMed 
glutamine transport ISO
Inferred from Sequence Orthology
more info
 
glycine betaine transport IDA
Inferred from Direct Assay
more info
PubMed 
neutral amino acid transport ISO
Inferred from Sequence Orthology
more info
 
positive regulation of RNA splicing ISO
Inferred from Sequence Orthology
more info
 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
regulation of cellular response to stress ISO
Inferred from Sequence Orthology
more info
 
sodium ion transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
axon IDA
Inferred from Direct Assay
more info
PubMed 
brush border IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
sarcolemma IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
sodium-coupled neutral amino acid transporter 2
Names
amino acid transporter A2
amino acid transporter cationic 2
amino acid transporter system A2
amino acid transporter, cationic 2 (low affinity)
system A amino acid transporter 2
system A transporter 1
system N amino acid transporter 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_181090.3NP_851604.2  sodium-coupled neutral amino acid transporter 2

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000187
    Related
    ENSRNOP00000031532.2, ENSRNOT00000039002.3

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005106.4 Reference Rnor_6.0 Primary Assembly

    Range
    138088654..138100869 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006242283.1XP_006242345.1  sodium-coupled neutral amino acid transporter 2 isoform X2

    Conserved Domains (1) summary
    cl00456
    Location:26439
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain
  2. XM_006242282.1XP_006242344.1  sodium-coupled neutral amino acid transporter 2 isoform X1

    Conserved Domains (2) summary
    COG0814
    Location:64516
    SdaC; Amino acid permease [Amino acid transport and metabolism]
    cl00456
    Location:69518
    SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

Alternate Rn_Celera

Genomic

  1. AC_000075.1 Alternate Rn_Celera

    Range
    124355437..124367606 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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