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Timm44 translocase of inner mitochondrial membrane 44 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29635, updated on 30-Sep-2021

Summary

Official Symbol
Timm44provided by RGD
Official Full Name
translocase of inner mitochondrial membrane 44provided by RGD
Primary source
RGD:3864
See related
EnsemblRapid:ENSRNOG00000001058
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
mouse homolog is a translocase of the inner mitochondrial membrane; can be up-regulated in hyperglycemic states [RGD, Feb 2006]
Expression
Biased expression in Heart (RPKM 430.7), Kidney (RPKM 319.8) and 9 other tissues See more
Orthologs
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Genomic context

See Timm44 in Genome Data Viewer
Location:
12p12
Exon count:
14
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 12 NC_051347.1 (2612581..2629374, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 12 NC_005111.4 (2517006..2533707)

Chromosome 12 - NC_051347.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120095870 Neighboring gene small nuclear RNA activating complex, polypeptide 2 Neighboring gene cortexin 1 Neighboring gene ELAV like RNA binding protein 1 Neighboring gene uncharacterized LOC102552452

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 
enables chaperone binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables chaperone binding IEA
Inferred from Electronic Annotation
more info
 
enables chaperone binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cardiac muscle cell differentiation IEP
Inferred from Expression Pattern
more info
PubMed 
involved_in intracellular protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in protein import into mitochondrial matrix IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein import into mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 
involved_in response to 3,3',5-triiodo-L-thyronine IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
located_in fibrillar center IEA
Inferred from Electronic Annotation
more info
 
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
 
is_active_in mitochondrial inner membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial matrix ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mitochondrial import inner membrane translocase subunit TIM44
Names
translocator of inner mitochondrial membrane 44

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017267.2NP_058963.2  mitochondrial import inner membrane translocase subunit TIM44

    Status: PROVISIONAL

    Source sequence(s)
    JACYVU010000223
    Related
    ENSRNOP00000001409.4, ENSRNOT00000001409.5
    Conserved Domains (1) summary
    TIGR00984
    Location:66443
    3a0801s03tim44; mitochondrial import inner membrane, translocase subunit

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051347.1 Reference mRatBN7.2 Primary Assembly

    Range
    2612581..2629374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039089299.1XP_038945227.1  mitochondrial import inner membrane translocase subunit TIM44 isoform X1

    Conserved Domains (1) summary
    TIGR00984
    Location:66258
    3a0801s03tim44; mitochondrial import inner membrane, translocase subunit
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