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Ube2e3 ubiquitin-conjugating enzyme E2E 3 [ Rattus norvegicus (Norway rat) ]

Gene ID: 295686, updated on 12-Aug-2018

Summary

Official Symbol
Ube2e3provided by RGD
Official Full Name
ubiquitin-conjugating enzyme E2E 3provided by RGD
Primary source
RGD:1308894
See related
Ensembl:ENSRNOG00000004544
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Brain (RPKM 216.8), Heart (RPKM 181.4) and 9 other tissues See more
Orthologs

Genomic context

See Ube2e3 in Genome Data Viewer
Location:
3q24
Exon count:
7
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (65815076..65876256)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 3 NC_005102.3 (72378562..72439742)

Chromosome 3 - NC_005102.4Genomic Context describing neighboring genes Neighboring gene high mobility group protein B1 pseudogene Neighboring gene similar to TF-1 apoptosis related protein 19 Neighboring gene protein argonaute 2-like Neighboring gene uncharacterized LOC102552587 Neighboring gene uncharacterized LOC103691829

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

  • Ubiquitin mediated proteolysis, organism-specific biosystem (from KEGG)
    Ubiquitin mediated proteolysis, organism-specific biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
  • Ubiquitin mediated proteolysis, conserved biosystem (from KEGG)
    Ubiquitin mediated proteolysis, conserved biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin conjugating enzyme activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ubiquitin conjugating enzyme activity ISO
Inferred from Sequence Orthology
more info
 
ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
protein K11-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein K11-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 
protein K11-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
 
protein K48-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein K48-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 
protein K48-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
 
protein K63-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 
protein K63-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ubiquitin-conjugating enzyme E2 E3
NP_001041322.2
XP_006234467.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001047857.3NP_001041322.2  ubiquitin-conjugating enzyme E2 E3

    See identical proteins and their annotated locations for NP_001041322.2

    Status: VALIDATED

    Source sequence(s)
    AABR07052608
    Related
    ENSRNOP00000006429.6, ENSRNOT00000006429.7
    Conserved Domains (1) summary
    pfam00179
    Location:65202
    UQ_con; Ubiquitin-conjugating enzyme

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005102.4 Reference Rnor_6.0 Primary Assembly

    Range
    65815076..65876256
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006234405.3XP_006234467.1  ubiquitin-conjugating enzyme E2 E3 isoform X1

    See identical proteins and their annotated locations for XP_006234467.1

    Conserved Domains (1) summary
    pfam00179
    Location:65202
    UQ_con; Ubiquitin-conjugating enzyme

Alternate Rn_Celera

Genomic

  1. AC_000071.1 Alternate Rn_Celera

    Range
    63252961..63308175
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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