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Ggt5 gamma-glutamyltransferase 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29566, updated on 22-May-2018
Official Symbol
Ggt5provided by RGD
Official Full Name
gamma-glutamyltransferase 5provided by RGD
Primary source
RGD:2684
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ggta1; Ggtla1
Summary
involved in protecting the lungs from stress due to oxidation or other types of toxics [RGD, Feb 2006]
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in Muscle (RPKM 21.6), Heart (RPKM 16.9) and 9 other tissues See more
Orthologs
See Ggt5 in Genome Data Viewer
Location:
20p12
Exon count:
5
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (13988444..14001296, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 19 NC_005118.3 (62302144..62302579, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 20 NC_005119.3 (16178488..16191069, complement)

Chromosome 20 - NC_005119.4Genomic Context describing neighboring genes Neighboring gene calcineurin binding protein 1 Neighboring gene uncharacterized LOC102556116 Neighboring gene sushi domain containing 2 Neighboring gene gamma-glutamyltransferase 1 Neighboring gene leucine rich repeat containing 75B

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Homology

Clone Names

  • MGC93485

Gene Ontology Provided by RGD

Function Evidence Code Pubs
glutathione hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
glutathione hydrolase activity ISO
Inferred from Sequence Orthology
more info
 
hypoglycin A gamma-glutamyl transpeptidase activity IEA
Inferred from Electronic Annotation
more info
 
leukotriene C4 gamma-glutamyl transferase activity IEA
Inferred from Electronic Annotation
more info
 
leukotriene-C(4) hydrolase ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
peptidyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cellular amino acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
fatty acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
glutathione biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
glutathione catabolic process IEA
Inferred from Electronic Annotation
more info
 
glutathione catabolic process ISO
Inferred from Sequence Orthology
more info
 
inflammatory response ISO
Inferred from Sequence Orthology
more info
 
leukotriene D4 biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
leukotriene biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
proteolysis IEA
Inferred from Electronic Annotation
more info
 
proteolysis ISO
Inferred from Sequence Orthology
more info
 
response to organonitrogen compound IEP
Inferred from Expression Pattern
more info
PubMed 
response to oxidative stress TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intrinsic component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
glutathione hydrolase 5 proenzyme
Names
GGL
GGT 5
GGT-rel
gamma-glutamyl leukotrienase
gamma-glutamyl transpeptidase-related enzyme
gamma-glutamyltransferase-like activity 1
gamma-glutamyltranspeptidase 5
glutathione hydrolase 5
leukotriene-C4 hydrolase
NP_062108.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019235.2NP_062108.2  glutathione hydrolase 5 proenzyme

    See identical proteins and their annotated locations for NP_062108.2

    Status: PROVISIONAL

    Source sequence(s)
    BC087018
    UniProtKB/TrEMBL
    Q5PQV0
    Conserved Domains (1) summary
    pfam01019
    Location:60567
    G_glu_transpept; Gamma-glutamyltranspeptidase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005119.4 Reference Rnor_6.0 Primary Assembly

    Range
    13988444..14001296 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000088.1 Alternate Rn_Celera

    Range
    14531284..14557667 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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