Format

Send to:

Choose Destination

Rhoc ras homolog family member C [ Rattus norvegicus (Norway rat) ]

Gene ID: 295342, updated on 3-Jan-2019

Summary

Official Symbol
Rhocprovided by RGD
Official Full Name
ras homolog family member Cprovided by RGD
Primary source
RGD:1304965
See related
Ensembl:ENSRNOG00000012630
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Kidney (RPKM 358.0), Heart (RPKM 322.2) and 9 other tissues See more
Orthologs

Genomic context

See Rhoc in Genome Data Viewer
Location:
2q34
Exon count:
6
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (207271692..207278010)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (226690856..226697174)

Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene TAFA chemokine like family member 3 Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent, 1J Neighboring gene Mov10 RISC complex RNA helicase Neighboring gene capping actin protein of muscle Z-line subunit alpha 1 Neighboring gene suppression of tumorigenicity 7-like Neighboring gene Wnt family member 2B

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
Rho protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament bundle assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin filament organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
apical junction assembly IEA
Inferred from Electronic Annotation
more info
 
apical junction assembly ISO
Inferred from Sequence Orthology
more info
 
cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
establishment or maintenance of actin cytoskeleton polarity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitotic cytokinesis ISO
Inferred from Sequence Orthology
more info
 
positive regulation of cell migration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of lipase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of protein homooligomerization IEA
Inferred from Electronic Annotation
more info
 
positive regulation of protein homooligomerization ISO
Inferred from Sequence Orthology
more info
 
positive regulation of stress fiber assembly ISO
Inferred from Sequence Orthology
more info
 
regulation of actin cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cell migration IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of cell shape IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
skeletal muscle satellite cell migration ISS
Inferred from Sequence or Structural Similarity
more info
 
wound healing, spreading of cells ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
cell cortex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cell division site IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cleavage furrow ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
stereocilium IEA
Inferred from Electronic Annotation
more info
 
stereocilium ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
rho-related GTP-binding protein RhoC
Names
ras homolog gene family, member C

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106461.1NP_001099931.1  rho-related GTP-binding protein RhoC

    See identical proteins and their annotated locations for NP_001099931.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474015
    Related
    ENSRNOP00000017254.3, ENSRNOT00000017254.6
    Conserved Domains (1) summary
    cd01870
    Location:5179
    RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

    Range
    207271692..207278010
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006233074.1XP_006233136.1  rho-related GTP-binding protein RhoC isoform X1

    See identical proteins and their annotated locations for XP_006233136.1

    UniProtKB/TrEMBL
    B2RYP0
    Conserved Domains (2) summary
    smart00174
    Location:8180
    RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
    cd01870
    Location:5179
    RhoA_like; Ras homology family A (RhoA)-like includes RhoA, RhoB and RhoC

Alternate Rn_Celera

Genomic

  1. AC_000070.1 Alternate Rn_Celera

    Range
    184753781..184759832
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center