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Man1a2 mannosidase, alpha, class 1A, member 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 295319, updated on 26-Jan-2021

Summary

Official Symbol
Man1a2provided by RGD
Official Full Name
mannosidase, alpha, class 1A, member 2provided by RGD
Primary source
RGD:1309767
See related
Ensembl:ENSRNOG00000015226
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Man1b
Expression
Biased expression in Liver (RPKM 210.2), Lung (RPKM 185.1) and 9 other tissues See more
Orthologs
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Genomic context

See Man1a2 in Genome Data Viewer
Location:
2q34
Exon count:
14
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (187947484..188096332, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (202891537..203043847, complement)

Chromosome 2 - NC_051337.1Genomic Context describing neighboring genes Neighboring gene ganglioside-induced differentiation-associated-protein 2 Neighboring gene uncharacterized LOC102554693 Neighboring gene terminal nucleotidyltransferase 5C Neighboring gene uncharacterized LOC120100896 Neighboring gene small nucleolar RNA SNORA17 Neighboring gene uncharacterized LOC120100606 Neighboring gene similar to zinc finger, DHHC domain containing 3 Neighboring gene uncharacterized LOC103691647

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
mannosyl-oligosaccharide 1,2-alpha-mannosidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
N-glycan processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
glycoprotein metabolic process ISO
Inferred from Sequence Orthology
more info
 
lung alveolus development ISO
Inferred from Sequence Orthology
more info
 
respiratory gaseous exchange by respiratory system ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Golgi membrane ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mannosyl-oligosaccharide 1,2-alpha-mannosidase IB
Names
mannosidase 1, beta
NP_001099922.1
XP_038957988.1
XP_038957989.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106452.1NP_001099922.1  mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

    See identical proteins and their annotated locations for NP_001099922.1

    Status: PROVISIONAL

    Source sequence(s)
    CH474015
    Related
    ENSRNOP00000060243.3, ENSRNOT00000067000.3
    Conserved Domains (2) summary
    pfam01532
    Location:187626
    Glyco_hydro_47; Glycosyl hydrolase family 47
    cl21478
    Location:107151
    ATP-synt_B; ATP synthase B/B' CF(0)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051337.1 Reference mRatBN7.2 Primary Assembly

    Range
    187947484..188096332 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039102060.1XP_038957988.1  mannosyl-oligosaccharide 1,2-alpha-mannosidase IB isoform X1

  2. XM_039102061.1XP_038957989.1  mannosyl-oligosaccharide 1,2-alpha-mannosidase IB isoform X2

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