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S100a1 S100 calcium binding protein A1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 295214, updated on 5-Aug-2018

Summary

Official Symbol
S100a1provided by RGD
Official Full Name
S100 calcium binding protein A1provided by RGD
Primary source
RGD:3614
See related
Ensembl:ENSRNOG00000012410
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
may play a role in signal transduction and myocardial function [RGD, Feb 2006]
Expression
Biased expression in Kidney (RPKM 98.7), Heart (RPKM 95.1) and 9 other tissues See more
Orthologs

Genomic context

See S100a1 in Genome Data Viewer
Location:
2q34
Exon count:
3
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (189900505..189905348, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (209330969..209336331, complement)

Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene SNAP-associated protein Neighboring gene chromatin target of PRMT1 Neighboring gene S100 calcium binding protein A13 Neighboring gene S100 calcium binding protein A16

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
ATPase binding IEA
Inferred from Electronic Annotation
more info
 
ATPase binding ISO
Inferred from Sequence Orthology
more info
 
S100 protein binding IEA
Inferred from Electronic Annotation
more info
 
S100 protein binding ISO
Inferred from Sequence Orthology
more info
 
calcium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
calcium-dependent protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity IDA
Inferred from Direct Assay
more info
PubMed 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
A band IDA
Inferred from Direct Assay
more info
PubMed 
I band IDA
Inferred from Direct Assay
more info
PubMed 
M band IDA
Inferred from Direct Assay
more info
PubMed 
Z disc IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
PubMed 
neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
sarcoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
sarcoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein S100-A1
Names
S-100 protein alpha chain
S-100 protein subunit alpha

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001007636.3NP_001007637.1  protein S100-A1

    See identical proteins and their annotated locations for NP_001007637.1

    Status: VALIDATED

    Source sequence(s)
    AC097705
    UniProtKB/Swiss-Prot
    P35467
    Related
    ENSRNOP00000017000.3, ENSRNOT00000017000.4
    Conserved Domains (2) summary
    cd05025
    Location:293
    S-100A1; S-100A1: S-100A1 domain found in proteins similar to S100A1. S100A1 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, to ...
    pfam13499
    Location:2876
    EF-hand_7; EF-hand domain pair

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

    Range
    189900505..189905348 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000070.1 Alternate Rn_Celera

    Range
    169929425..169934268 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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