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Map1b microtubule-associated protein 1B [ Rattus norvegicus (Norway rat) ]

Gene ID: 29456, updated on 5-May-2019

Summary

Official Symbol
Map1bprovided by RGD
Official Full Name
microtubule-associated protein 1Bprovided by RGD
Primary source
RGD:3043
See related
Ensembl:ENSRNOG00000017428
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Mtap1b
Summary
binds microtubules and may function as microtubule cross-linkers [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 1000.6), Heart (RPKM 118.4) and 4 other tissues See more
Orthologs

Genomic context

See Map1b in Genome Data Viewer
Location:
2q12
Exon count:
7
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (29675391..29768750, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (48837124..48930483, complement)

Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene pentatricopeptide repeat domain 2 Neighboring gene mitochondrial ribosomal protein S27 Neighboring gene uncharacterized LOC108349930 Neighboring gene uncharacterized LOC102553545 Neighboring gene hypothetical LOC499517

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • Wnt Signaling Pathway NetPath, organism-specific biosystem (from WikiPathways)
    Wnt Signaling Pathway NetPath, organism-specific biosystemWnt family of proteins are a large family of cysteine-rich secreted glycoproteins that regulate cell-cell interactions. They bind to members of the Frizzled family of 7 transmembrane receptors. Bindi...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
actin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
actin binding IDA
Inferred from Direct Assay
more info
PubMed 
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule binding IDA
Inferred from Direct Assay
more info
PubMed 
microtubule binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
phospholipid binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-containing complex binding IDA
Inferred from Direct Assay
more info
PubMed 
tubulin binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
axon extension IEA
Inferred from Electronic Annotation
more info
 
axon extension ISO
Inferred from Sequence Orthology
more info
PubMed 
axonogenesis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
axonogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular process ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to growth factor stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to peptide hormone stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
dendrite development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite development ISO
Inferred from Sequence Orthology
more info
PubMed 
developmental maturation IEP
Inferred from Expression Pattern
more info
PubMed 
establishment of monopolar cell polarity IEA
Inferred from Electronic Annotation
more info
 
establishment of monopolar cell polarity ISO
Inferred from Sequence Orthology
more info
PubMed 
induction of synaptic plasticity by chemical substance IEP
Inferred from Expression Pattern
more info
PubMed 
microtubule bundle formation IDA
Inferred from Direct Assay
more info
PubMed 
microtubule bundle formation ISO
Inferred from Sequence Orthology
more info
PubMed 
microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion transport along microtubule IEA
Inferred from Electronic Annotation
more info
 
mitochondrion transport along microtubule ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of intracellular transport IEA
Inferred from Electronic Annotation
more info
 
negative regulation of intracellular transport ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of microtubule depolymerization IDA
Inferred from Direct Assay
more info
PubMed 
nervous system development IEP
Inferred from Expression Pattern
more info
PubMed 
neuron development IEP
Inferred from Expression Pattern
more info
PubMed 
peripheral nervous system axon regeneration IEP
Inferred from Expression Pattern
more info
PubMed 
positive regulation of axon extension IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of microtubule polymerization IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of neuron differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of microtubule depolymerization IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
response to axon injury IEP
Inferred from Expression Pattern
more info
PubMed 
response to carbohydrate IEP
Inferred from Expression Pattern
more info
PubMed 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
response to estradiol IEP
Inferred from Expression Pattern
more info
PubMed 
response to inorganic substance IEP
Inferred from Expression Pattern
more info
PubMed 
response to insecticide IEP
Inferred from Expression Pattern
more info
PubMed 
response to mechanical stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
response to nutrient levels IEP
Inferred from Expression Pattern
more info
PubMed 
response to vitamin A IEP
Inferred from Expression Pattern
more info
PubMed 
response to wounding IEP
Inferred from Expression Pattern
more info
PubMed 
synapse assembly IEP
Inferred from Expression Pattern
more info
PubMed 
Component Evidence Code Pubs
apical dendrite IDA
Inferred from Direct Assay
more info
PubMed 
axon IDA
Inferred from Direct Assay
more info
PubMed 
basal dendrite IDA
Inferred from Direct Assay
more info
PubMed 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cell projection IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeleton IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol ISO
Inferred from Sequence Orthology
more info
PubMed 
dendrite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
dendrite ISO
Inferred from Sequence Orthology
more info
PubMed 
dendritic spine IEA
Inferred from Electronic Annotation
more info
 
growth cone IDA
Inferred from Direct Assay
more info
PubMed 
hippocampal mossy fiber IDA
Inferred from Direct Assay
more info
PubMed 
microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule IDA
Inferred from Direct Assay
more info
PubMed 
microtubule associated complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule associated complex IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuronal cell body IDA
Inferred from Direct Assay
more info
PubMed 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
PubMed 
perikaryon IDA
Inferred from Direct Assay
more info
PubMed 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
photoreceptor outer segment IEA
Inferred from Electronic Annotation
more info
 
photoreceptor outer segment ISO
Inferred from Sequence Orthology
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
postsynaptic density IDA
Inferred from Direct Assay
more info
PubMed 
postsynaptic density ISO
Inferred from Sequence Orthology
more info
PubMed 
somatodendritic compartment IDA
Inferred from Direct Assay
more info
PubMed 
synapse IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
varicosity IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
microtubule-associated protein 1B
Names
MAP-1B
neuraxin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019217.1NP_062090.1  microtubule-associated protein 1B

    Status: PROVISIONAL

    Source sequence(s)
    AA925503, BF286433, BG378086, BG665276, CA503854, CA510735, CA510940, CB576609, CB579120, CB580055, CB583564, CB584802, CB610210, CB810012, CF977184, CO393350, X60370
    UniProtKB/Swiss-Prot
    P15205
    Related
    ENSRNOP00000023460.5, ENSRNOT00000023460.5
    Conserved Domains (3) summary
    PTZ00121
    Location:5311158
    PTZ00121; MAEBL; Provisional
    PHA03247
    Location:20952348
    PHA03247; large tegument protein UL36; Provisional
    pfam05109
    Location:15431875
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

    Range
    29675391..29768750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000070.1 Alternate Rn_Celera

    Range
    26841920..26934955 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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