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C20h6orf89 similar to human chromosome 6 open reading frame 89 [ Rattus norvegicus (Norway rat) ]

Gene ID: 294311, updated on 10-Feb-2026
Official Symbol
C20h6orf89provided by RGD
Official Full Name
similar to human chromosome 6 open reading frame 89provided by RGD
Primary source
RGD:735065
See related
Ensembl:ENSRNOG00000000524 AllianceGenome:RGD:735065
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD735065
Summary
Predicted to be involved in several processes, including chromatin remodeling; epithelial cell proliferation; and wound healing. Predicted to act upstream of or within several processes, including collagen metabolic process; connective tissue replacement; and response to bleomycin. Predicted to be located in several cellular components, including midbody; nucleolus; and plasma membrane. Predicted to be active in Golgi membrane. Orthologous to human C6orf89 (chromosome 6 open reading frame 89). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Biased expression in Liver (RPKM 163.6), Heart (RPKM 111.0) and 9 other tissues See more
Orthologs
all
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Try the new Transcripts and proteins table
See C20h6orf89 in Genome Data Viewer
Location:
20p12
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (7324105..7368482)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (7322483..7362054)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (6869870..6910022)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102547155 Neighboring gene peptidylprolyl isomerase like 1 Neighboring gene transfer RNA threonine (anticodon AGU) 18 Neighboring gene uncharacterized LOC120098949 Neighboring gene peptidase inhibitor 16 Neighboring gene uncharacterized LOC134483863 Neighboring gene mitochondrial carrier 1

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Cloning of a novel protein interacting with BRS-3 and its effects in wound repair of bronchial epithelial cells. Liu HJ, et al. PLoS One, 2011. PMID 21857995, Free PMC Article
  2. C6orf89 encodes three distinct HDAC enhancers that function in the nucleolus, the golgi and the midbody. Lalioti VS, et al. J Cell Physiol, 2013 Sep. PMID 23460338
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Clone Names

  • MGC72991

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in chromatin remodeling ISO
Inferred from Sequence Orthology
more info
  
involved_in chromatin remodeling ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in epithelial cell proliferation ISO
Inferred from Sequence Orthology
more info
  
involved_in epithelial cell proliferation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in positive regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of cell cycle ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in wound healing ISO
Inferred from Sequence Orthology
more info
  
involved_in wound healing ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in midbody ISO
Inferred from Sequence Orthology
more info
  
located_in midbody ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
Preferred Names
bombesin receptor-activated protein C6orf89 homolog
Names
uncharacterized protein C6orf89 homolog

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_199379.3 → NP_955411.1  bombesin receptor-activated protein C6orf89 homolog

    See identical proteins and their annotated locations for NP_955411.1

    Status: VALIDATED

    Source sequence(s)
    BC062242, JAXUCZ010000020
    UniProtKB/Swiss-Prot
    Q6P6G2
    UniProtKB/TrEMBL
    A0ABK0LAZ1, A6JJU4
    Related
    ENSRNOP00000084100.1, ENSRNOT00000102727.2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    7324105..7368482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039098522.2 → XP_038954450.1  bombesin receptor-activated protein C6orf89 homolog isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZPM7

  2. XM_039098520.2 → XP_038954448.1  bombesin receptor-activated protein C6orf89 homolog isoform X2

    UniProtKB/TrEMBL
    A0A8I5ZPM7

  3. XM_039098528.2 → XP_038954456.1  bombesin receptor-activated protein C6orf89 homolog isoform X6

    UniProtKB/TrEMBL
    A0A8L2PYE9, A0ABK0LAZ1
    Related
    ENSRNOP00000000631.4, ENSRNOT00000000631.6

  4. XM_063279034.1 → XP_063135104.1  bombesin receptor-activated protein C6orf89 homolog isoform X8

  5. XM_063279036.1 → XP_063135106.1  bombesin receptor-activated protein C6orf89 homolog isoform X10

  6. XM_006256182.5 → XP_006256244.1  bombesin receptor-activated protein C6orf89 homolog isoform X5

    UniProtKB/TrEMBL
    A0A1W2Q646, A0ABK0LAZ1
    Related
    ENSRNOP00000076127.3, ENSRNOT00000093638.3

  7. XM_039098529.2 → XP_038954457.1  bombesin receptor-activated protein C6orf89 homolog isoform X7

  8. XM_063279035.1 → XP_063135105.1  bombesin receptor-activated protein C6orf89 homolog isoform X9

  9. XM_006256172.5 → XP_006256234.1  bombesin receptor-activated protein C6orf89 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZPM7

  10. XM_063279032.1 → XP_063135102.1  bombesin receptor-activated protein C6orf89 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZPM7

  11. XM_063279031.1 → XP_063135101.1  bombesin receptor-activated protein C6orf89 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZPM7

  12. XM_063279033.1 → XP_063135103.1  bombesin receptor-activated protein C6orf89 homolog isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZPM7
    Related
    ENSRNOP00000076205.3, ENSRNOT00000093736.3

  13. XM_006256181.5 → XP_006256243.1  bombesin receptor-activated protein C6orf89 homolog isoform X4

    UniProtKB/TrEMBL
    A0A1W2Q6A8

  14. XM_039098524.2 → XP_038954452.1  bombesin receptor-activated protein C6orf89 homolog isoform X3

    UniProtKB/TrEMBL
    A0A8I5ZPM7

RNA

  1. XR_010060642.1 RNA Sequence

  2. XR_010060641.1 RNA Sequence

  3. XR_010060643.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6P6G2.1 GenPept UniProtKB/Swiss-Prot:Q6P6G2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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