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Psmb5 proteasome subunit beta 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29425, updated on 3-Jun-2018
Official Symbol
Psmb5provided by RGD
Official Full Name
proteasome subunit beta 5provided by RGD
Primary source
RGD:61879
See related
Ensembl:ENSRNOG00000013386
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
mouse homolog plays a role in production of peptides for MHC class I antigen presentation [RGD, Feb 2006]
Expression
Biased expression in Muscle (RPKM 533.6), Heart (RPKM 450.6) and 9 other tissues See more
Orthologs
See Psmb5 in Genome Data Viewer
Location:
15p13
Exon count:
3
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (33259039..33263634, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 15 NC_005114.3 (37143058..37147105, complement)

Chromosome 15 - NC_005114.4Genomic Context describing neighboring genes Neighboring gene ajuba LIM protein Neighboring gene similar to RIKEN cDNA 4931414P19 Neighboring gene proteasome subunit beta 11 Neighboring gene cadherin 24

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptidase activity ISO
Inferred from Sequence Orthology
more info
 
threonine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
proteasomal protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasomal ubiquitin-independent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 
proteasome-mediated ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
proteolysis ISO
Inferred from Sequence Orthology
more info
 
response to oxidative stress IEA
Inferred from Electronic Annotation
more info
 
response to oxidative stress ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
centrosome IEA
Inferred from Electronic Annotation
more info
 
centrosome ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
proteasome complex ISO
Inferred from Sequence Orthology
more info
 
proteasome core complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
proteasome core complex IEA
Inferred from Electronic Annotation
more info
 
proteasome core complex ISO
Inferred from Sequence Orthology
more info
 
proteasome core complex ISS
Inferred from Sequence or Structural Similarity
more info
 
proteasome core complex, beta-subunit complex ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
proteasome subunit beta type-5
Names
macropain epsilon chain
multicatalytic endopeptidase complex epsilon chain
proteasome (prosome, macropain) subunit, beta type 5
proteasome beta 5 subunit
proteasome beta type subunit 5
proteasome chain 6
proteasome epsilon chain
proteasome subunit X
NP_001099197.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001105727.2NP_001099197.2  proteasome subunit beta type-5

    See identical proteins and their annotated locations for NP_001099197.2

    Status: VALIDATED

    Source sequence(s)
    AI602737, CB783917
    UniProtKB/Swiss-Prot
    P28075
    UniProtKB/TrEMBL
    G3V7Q6
    Related
    ENSRNOP00000018005.4, ENSRNOT00000018005.7
    Conserved Domains (2) summary
    PTZ00488
    Location:29263
    PTZ00488; Proteasome subunit beta type-5; Provisional
    cd03761
    Location:60247
    proteasome_beta_type_5; proteasome beta type-5 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005114.4 Reference Rnor_6.0 Primary Assembly

    Range
    33259039..33263634 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000083.1 Alternate Rn_Celera

    Range
    27651286..27655779 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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