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Nkx1-2 NK1 homeobox 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 293568, updated on 21-Jul-2018

Summary

Official Symbol
Nkx1-2provided by RGD
Official Full Name
NK1 homeobox 2provided by RGD
Primary source
RGD:1306744
See related
Ensembl:ENSRNOG00000017006
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Kidney (RPKM 20.7), Liver (RPKM 9.2) and 3 other tissues See more
Orthologs

Genomic context

See Nkx1-2 in Genome Data Viewer
Location:
1q41
Exon count:
2
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (204603116..204605552, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (211596785..211599221, complement)

Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L27 pseudogene Neighboring gene ornithine aminotransferase Neighboring gene phospholysine phosphohistidine inorganic pyrophosphate phosphatase Neighboring gene family with sequence similarity 53, member B Neighboring gene uncharacterized LOC102552031

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
NK1 transcription factor-related protein 2
Names
NK1 transcription factor related, locus 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001170476.1NP_001163947.1  NK1 transcription factor-related protein 2

    See identical proteins and their annotated locations for NP_001163947.1

    Status: VALIDATED

    Source sequence(s)
    AABR07005888
    UniProtKB/TrEMBL
    D3Z9E2
    Related
    ENSRNOP00000022904.3, ENSRNOT00000022904.4
    Conserved Domains (1) summary
    pfam00046
    Location:160212
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

    Range
    204603116..204605552 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000069.1 Alternate Rn_Celera

    Range
    185133266..185135702 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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