Cep89 centrosomal protein 89 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Cep89provided by RGD
Official Full Name: centrosomal protein 89provided by RGD
Primary source: RGD:1311730
See related: Ensembl:ENSRNOG00000012140 AllianceGenome:RGD:1311730
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ccdc123; RGD1311730
Summary: Predicted to be involved in mitochondrial cytochrome c oxidase assembly and non-motile cilium assembly. Predicted to be located in several cellular components, including microtubule cytoskeleton; mitochondrial intermembrane space; and nuclear body. Predicted to be part of ciliary transition fiber. Predicted to be active in centriole. Orthologous to human CEP89 (centrosomal protein 89). [provided by Alliance of Genome Resources, Jul 2025]
Expression: Biased expression in Thymus (RPKM 90.9), Adrenal (RPKM 39.4) and 9 other tissues See more
Orthologs: all
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Genomic context

Location:: 1q21

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	1	NC_086019.1 (97195116..97237015)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	1	NC_051336.1 (88058211..88100114)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	1	NC_005100.4 (91663723..91705979)

Chromosome 1 - NC_086019.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

AU047079 (e-PCR)
- UniSTS:110862

AI230035 (e-PCR)
- UniSTS:250603

Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in chemical synaptic transmission	IEA Inferred from Electronic Annotation more info
involved_in cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in cilium assembly	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in cilium assembly	ISO Inferred from Sequence Orthology more info
involved_in mitochondrial respiratory chain complex IV assembly	IEA Inferred from Electronic Annotation more info
involved_in mitochondrial respiratory chain complex IV assembly	ISO Inferred from Sequence Orthology more info
involved_in mitochondrion organization	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitochondrion organization	IEA Inferred from Electronic Annotation more info
involved_in non-motile cilium assembly	IEA Inferred from Electronic Annotation more info
involved_in non-motile cilium assembly	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in centriole	IBA Inferred from Biological aspect of Ancestor more info
located_in centriole	IEA Inferred from Electronic Annotation more info
located_in centriole	ISO Inferred from Sequence Orthology more info
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in centrosome	ISO Inferred from Sequence Orthology more info
located_in ciliary basal body	IEA Inferred from Electronic Annotation more info
located_in ciliary basal body	ISO Inferred from Sequence Orthology more info
part_of ciliary transition fiber	IBA Inferred from Biological aspect of Ancestor more info
part_of ciliary transition fiber	IEA Inferred from Electronic Annotation more info
part_of ciliary transition fiber	ISO Inferred from Sequence Orthology more info
located_in cytosol	IEA Inferred from Electronic Annotation more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
located_in mitochondrial intermembrane space	IEA Inferred from Electronic Annotation more info
located_in mitochondrial intermembrane space	ISO Inferred from Sequence Orthology more info
located_in motile cilium	IEA Inferred from Electronic Annotation more info
located_in motile cilium	ISO Inferred from Sequence Orthology more info
located_in non-motile cilium	IEA Inferred from Electronic Annotation more info
located_in non-motile cilium	ISO Inferred from Sequence Orthology more info
located_in spindle pole	IEA Inferred from Electronic Annotation more info
located_in spindle pole	ISO Inferred from Sequence Orthology more info
located_in synapse	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: centrosomal protein of 89 kDa

Names: centrosomal protein 89kDa; coiled-coil domain containing 123

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001394861.1 → NP_001381790.1 centrosomal protein of 89 kDa

Status: VALIDATED

Source sequence(s)

JAXUCZ010000001

UniProtKB/TrEMBL

A0A0G2JZG8

Related

ENSRNOP00000071041.2, ENSRNOT00000089587.3

Conserved Domains (1) summary

COG1196
Location:362 → 713

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]