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Ddx19a DEAD-box helicase 19A [ Rattus norvegicus (Norway rat) ]

Gene ID: 292022, updated on 23-Apr-2026
Official Symbol
Ddx19aprovided by RGD
Official Full Name
DEAD-box helicase 19Aprovided by RGD
Primary source
RGD:1303136
See related
Ensembl:ENSRNOG00000018033 AllianceGenome:RGD:1303136
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ddx19; ZD10B
Summary
Predicted to enable ATP binding activity and hydrolase activity. Involved in positive regulation of apoptotic process and response to zinc ion. Orthologous to human DDX19A (DEAD-box helicase 19A). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Biased expression in Kidney (RPKM 566.8), Thymus (RPKM 158.3) and 9 other tissues See more
Orthologs
all
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Try the new Transcripts and proteins table
See Ddx19a in Genome Data Viewer
Location:
19q12
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (55851854..55872209, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (38942497..38962853, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (43251510..43271865)

Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483368 Neighboring gene ST3 beta-galactoside alpha-2,3-sialyltransferase 2 Neighboring gene DEAD-box helicase 19B Neighboring gene alanyl-tRNA synthetase 1 Neighboring gene exosome component 6

Go to nucleotide: Graphics FASTA GenBank

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Related articles in PubMed

  1. Differentially expressed genes execute zinc-induced apoptosis in precancerous esophageal epithelium of zinc-deficient rats. Ishii H, et al. Oncogene, 2004 Oct 21. PMID 15361827
  2. Defining the membrane proteome of NK cells. Ghosh D, et al. J Mass Spectrom, 2010 Jan. PMID 19946888
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Preferred Names
ATP-dependent RNA helicase DDX19A
Names
DEAD (Asp-Glu-Ala-As) box polypeptide 19A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19
DEAD (Asp-Glu-Ala-Asp) box polypeptide 19a
zinc responsive protein ZD10B
NP_001005381.2
XP_008770712.1
XP_063134007.1
XP_063134008.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005381.2 → NP_001005381.2  ATP-dependent RNA helicase DDX19A

    See identical proteins and their annotated locations for NP_001005381.2

    Status: VALIDATED

    Source sequence(s)
    BC079094, CB582878
    UniProtKB/TrEMBL
    A0A8J8Y6U2, F7DP80, Q68FX3
    Related
    ENSRNOP00000024793.9, ENSRNOT00000024793.9
    Conserved Domains (2) summary
    cd18787
    Location:306 → 442
    SF2_C_DEAD; C-terminal helicase domain of the DEAD box helicases
    cl28899
    Location:74 → 302
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086037.1 Reference GRCr8

    Range
    55851854..55872209 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_063277937.1 → XP_063134007.1  ATP-dependent RNA helicase DDX19A isoform X1

    UniProtKB/TrEMBL
    A0A8J8Y6U2

  2. XM_063277938.1 → XP_063134008.1  ATP-dependent RNA helicase DDX19A isoform X1

    UniProtKB/TrEMBL
    A0A8J8Y6U2

  3. XM_008772490.4 → XP_008770712.1  ATP-dependent RNA helicase DDX19A isoform X2

    Conserved Domains (2) summary
    cd18787
    Location:216 → 352
    SF2_C_DEAD; C-terminal helicase domain of the DEAD box helicases
    cl28899
    Location:9 → 212
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
Nucleotide Protein Strain
Heading Accession and Version

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