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Hhip Hedgehog-interacting protein [ Rattus norvegicus (Norway rat) ]

Gene ID: 291936, updated on 30-Aug-2020

Summary

Official Symbol
Hhipprovided by RGD
Official Full Name
Hedgehog-interacting proteinprovided by RGD
Primary source
RGD:1564108
See related
Ensembl:ENSRNOG00000018268
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1564108
Expression
Biased expression in Lung (RPKM 167.1), Brain (RPKM 46.0) and 6 other tissues See more
Orthologs

Genomic context

See Hhip in Genome Data Viewer
Location:
19q11
Exon count:
13
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (31525134..31614487)
106 current Rn_Celera (GCF_000002265.2) 19 AC_000087.1 (27371896..27460078)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 19 NC_005118.3 (42430120..42518700)

Chromosome 19 - NC_005118.4Genomic Context describing neighboring genes Neighboring gene glycophorin A Neighboring gene uncharacterized LOC103694973 Neighboring gene uncharacterized LOC102549515 Neighboring gene uncharacterized LOC102549584 Neighboring gene anaphase promoting complex subunit 10

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
hedgehog family protein binding ISO
Inferred from Sequence Orthology
more info
 
molecular_function ND
No biological Data available
more info
 
zinc ion binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
animal organ morphogenesis ISO
Inferred from Sequence Orthology
more info
 
dorsal/ventral pattern formation ISO
Inferred from Sequence Orthology
more info
 
epithelial tube branching involved in lung morphogenesis ISO
Inferred from Sequence Orthology
more info
 
negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of signal transduction ISO
Inferred from Sequence Orthology
more info
 
negative regulation of smoothened signaling pathway ISO
Inferred from Sequence Orthology
more info
 
neuroblast proliferation ISO
Inferred from Sequence Orthology
more info
 
regulation of fibroblast growth factor receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
 
signal transduction ISO
Inferred from Sequence Orthology
more info
 
skeletal system morphogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cell surface ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
hedgehog-interacting protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191817.1NP_001178746.1  hedgehog-interacting protein precursor

    Status: PROVISIONAL

    Source sequence(s)
    AABR07043609, AABR07043611
    UniProtKB/TrEMBL
    D3ZGL3
    Related
    ENSRNOP00000024616.5, ENSRNOT00000024616.7
    Conserved Domains (2) summary
    pfam03024
    Location:38220
    Folate_rec; Folate receptor family
    pfam07995
    Location:226428
    GSDH; Glucose / Sorbosone dehydrogenase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005118.4 Reference Rnor_6.0 Primary Assembly

    Range
    31525134..31614487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000087.1 Alternate Rn_Celera

    Range
    27371896..27460078
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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