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Fdx1 ferredoxin 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 29189, updated on 2-Oct-2018

Summary

Official Symbol
Fdx1provided by RGD
Official Full Name
ferredoxin 1provided by RGD
Primary source
RGD:62036
See related
Ensembl:ENSRNOG00000012123
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary
precursor of adrenodoxin [RGD, Feb 2006]
Expression
Biased expression in Adrenal (RPKM 8606.5) and Liver (RPKM 665.8) See more
Orthologs

Genomic context

See Fdx1 in Genome Data Viewer
Location:
8q24
Exon count:
4
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (56373729..56393199, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 8 NC_005107.3 (54958315..54977222, complement)

Chromosome 8 - NC_005107.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103693093 Neighboring gene Rho GTPase activating protein 20 Neighboring gene mitochondrial ribosomal protein L1-like Neighboring gene low molecular weight phosphotyrosine protein phosphatase pseudogene Neighboring gene radixin

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 
2 iron, 2 sulfur cluster binding ISO
Inferred from Sequence Orthology
more info
 
2 iron, 2 sulfur cluster binding ISS
Inferred from Sequence or Structural Similarity
more info
 
contributes_to NADPH-adrenodoxin reductase activity IDA
Inferred from Direct Assay
more info
PubMed 
contributes_to cholesterol monooxygenase (side-chain-cleaving) activity IDA
Inferred from Direct Assay
more info
PubMed 
electron transfer activity IDA
Inferred from Direct Assay
more info
PubMed 
electron transfer activity IEA
Inferred from Electronic Annotation
more info
 
electron transfer activity ISO
Inferred from Sequence Orthology
more info
 
enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
iron ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
NADPH oxidation IDA
Inferred from Direct Assay
more info
PubMed 
adrenal gland development IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to cAMP IEA
Inferred from Electronic Annotation
more info
 
cellular response to cAMP ISO
Inferred from Sequence Orthology
more info
 
cellular response to epinephrine stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to forskolin IEA
Inferred from Electronic Annotation
more info
 
cellular response to forskolin ISO
Inferred from Sequence Orthology
more info
 
cellular response to leptin stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to organic cyclic compound IEP
Inferred from Expression Pattern
more info
PubMed 
cholesterol metabolic process IEA
Inferred from Electronic Annotation
more info
 
cholesterol metabolic process ISO
Inferred from Sequence Orthology
more info
 
cholesterol metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
electron transport chain IEA
Inferred from Electronic Annotation
more info
 
hormone biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
hormone biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
hormone biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of oxidoreductase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of catalytic activity IDA
Inferred from Direct Assay
more info
PubMed 
response to gonadotropin IEP
Inferred from Expression Pattern
more info
PubMed 
response to leptin IEP
Inferred from Expression Pattern
more info
PubMed 
steroid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrial crista IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrial matrix IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
adrenodoxin, mitochondrial
Names
adrenal ferredoxin

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017126.1NP_058822.1  adrenodoxin, mitochondrial precursor

    See identical proteins and their annotated locations for NP_058822.1

    Status: PROVISIONAL

    Source sequence(s)
    D50436
    UniProtKB/Swiss-Prot
    P24483
    Related
    ENSRNOP00000016263.1, ENSRNOT00000016263.3
    Conserved Domains (1) summary
    cl00159
    Location:71174
    fer2; 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis ...

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005107.4 Reference Rnor_6.0 Primary Assembly

    Range
    56373729..56393199 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000076.1 Alternate Rn_Celera

    Range
    51793129..51811786 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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