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Cd36 CD36 molecule [ Rattus norvegicus (Norway rat) ]

Gene ID: 29184, updated on 10-Oct-2019

Summary

Official Symbol
Cd36provided by RGD
Official Full Name
CD36 moleculeprovided by RGD
Primary source
RGD:2301
See related
Ensembl:ENSRNOG00000040108
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fat; RGD1562323
Summary
fatty acid translocase; involved in long-chain fatty acid (LCFA) transport; important in fatty acid metabolism and insulin function [RGD, Feb 2006]
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in Heart (RPKM 5293.2), Spleen (RPKM 2488.5) and 6 other tissues See more

Genomic context

See Cd36 in Genome Data Viewer
Location:
4q11
Exon count:
14
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (14150309..14191498)
106 current Rn_Celera (GCF_000002265.2) 4 AC_000072.1 (12880238..12941086)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (14125297..14166434)

Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene similar to fatty acid translocase/CD36 Neighboring gene MLV-related proviral Env polyprotein-like Neighboring gene uncharacterized LOC108350653 Neighboring gene platelet glycoprotein 4-like

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Clone Names

  • MGC91634, MGC108510

Gene Ontology Provided by RGD

Function Evidence Code Pubs
Toll-like receptor binding ISO
Inferred from Sequence Orthology
more info
PubMed 
amyloid-beta binding ISO
Inferred from Sequence Orthology
more info
PubMed 
high-density lipoprotein particle binding ISO
Inferred from Sequence Orthology
more info
PubMed 
lipid binding ISO
Inferred from Sequence Orthology
more info
PubMed 
lipoprotein particle binding ISO
Inferred from Sequence Orthology
more info
PubMed 
lipoteichoic acid receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
low-density lipoprotein particle binding ISO
Inferred from Sequence Orthology
more info
PubMed 
low-density lipoprotein particle receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
oleic acid binding IDA
Inferred from Direct Assay
more info
PubMed 
oxidised low-density lipoprotein particle receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
PubMed 
scavenger receptor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
scavenger receptor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
thrombospondin receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
transforming growth factor beta binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
amyloid fibril formation ISO
Inferred from Sequence Orthology
more info
PubMed 
amyloid fibril formation ISS
Inferred from Sequence or Structural Similarity
more info
 
amyloid-beta clearance by cellular catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
amyloid-beta clearance by cellular catabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
apoptotic cell clearance ISO
Inferred from Sequence Orthology
more info
PubMed 
cGMP-mediated signaling ISO
Inferred from Sequence Orthology
more info
PubMed 
cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
cell surface receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
PubMed 
cell-cell adhesion via plasma-membrane adhesion molecules IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to amyloid-beta ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to bacterial lipopeptide ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to diacyl bacterial lipopeptide ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to diacyl bacterial lipopeptide ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to hydroperoxide ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to insulin stimulus IEP
Inferred from Expression Pattern
more info
PubMed 
cellular response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to lipoteichoic acid ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to low-density lipoprotein particle stimulus ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular response to low-density lipoprotein particle stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to oxidised low-density lipoprotein particle stimulus ISO
Inferred from Sequence Orthology
more info
PubMed 
cholesterol import ISO
Inferred from Sequence Orthology
more info
PubMed 
cholesterol import ISS
Inferred from Sequence or Structural Similarity
more info
 
cholesterol transport ISO
Inferred from Sequence Orthology
more info
PubMed 
defense response to Gram-positive bacterium ISO
Inferred from Sequence Orthology
more info
PubMed 
digestive tract development IEP
Inferred from Expression Pattern
more info
PubMed 
eating behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
energy homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
energy homeostasis ISO
Inferred from Sequence Orthology
more info
PubMed 
fatty acid metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
fatty acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
fatty acid oxidation IMP
Inferred from Mutant Phenotype
more info
PubMed 
fatty acid transport IDA
Inferred from Direct Assay
more info
PubMed 
fatty acid transport IEP
Inferred from Expression Pattern
more info
PubMed 
fatty acid transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
glucose homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune response IEA
Inferred from Electronic Annotation
more info
 
interleukin-1 beta secretion ISO
Inferred from Sequence Orthology
more info
PubMed 
interleukin-1 beta secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
intestinal absorption ISO
Inferred from Sequence Orthology
more info
PubMed 
intestinal absorption ISS
Inferred from Sequence or Structural Similarity
more info
 
intestinal cholesterol absorption ISO
Inferred from Sequence Orthology
more info
PubMed 
intestinal cholesterol absorption ISS
Inferred from Sequence or Structural Similarity
more info
 
lipid storage ISO
Inferred from Sequence Orthology
more info
PubMed 
lipoprotein transport ISO
Inferred from Sequence Orthology
more info
PubMed 
long-chain fatty acid import ISO
Inferred from Sequence Orthology
more info
PubMed 
long-chain fatty acid import ISS
Inferred from Sequence or Structural Similarity
more info
 
long-chain fatty acid metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
long-chain fatty acid transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
low-density lipoprotein particle clearance ISO
Inferred from Sequence Orthology
more info
PubMed 
low-density lipoprotein particle mediated signaling ISO
Inferred from Sequence Orthology
more info
PubMed 
maternal placenta development IEP
Inferred from Expression Pattern
more info
PubMed 
negative regulation of angiogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of gene expression ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of protein import into nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of systemic arterial blood pressure IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of transcription by RNA polymerase II ISO
Inferred from Sequence Orthology
more info
PubMed 
nitric oxide mediated signal transduction ISO
Inferred from Sequence Orthology
more info
PubMed 
oxidised low-density lipoprotein particle clearance ISO
Inferred from Sequence Orthology
more info
PubMed 
phagocytosis, recognition ISO
Inferred from Sequence Orthology
more info
PubMed 
plasma lipoprotein particle clearance ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of MAPK cascade ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of NF-kappaB transcription factor activity ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of NLRP3 inflammasome complex assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of NLRP3 inflammasome complex assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of blood coagulation ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of blood microparticle formation ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of cell death ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of cell-matrix adhesion ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of cholesterol storage ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of cold-induced thermogenesis ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of cold-induced thermogenesis ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of cytokine secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of cytosolic calcium ion concentration ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of interleukin-12 production ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of interleukin-6 production ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of macrophage cytokine production ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of macrophage derived foam cell differentiation ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of nitric oxide biosynthetic process ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of peptidyl-tyrosine phosphorylation ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of phagocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of phagocytosis, engulfment ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of reactive oxygen species biosynthetic process ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of reactive oxygen species metabolic process ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of triglyceride metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of tumor necrosis factor production ISO
Inferred from Sequence Orthology
more info
PubMed 
receptor internalization ISO
Inferred from Sequence Orthology
more info
PubMed 
receptor internalization ISS
Inferred from Sequence or Structural Similarity
more info
 
receptor-mediated endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
receptor-mediated endocytosis ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of action potential ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of removal of superoxide radicals ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of toll-like receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
PubMed 
response to activity IEP
Inferred from Expression Pattern
more info
PubMed 
response to bacterium ISO
Inferred from Sequence Orthology
more info
PubMed 
response to drug IEP
Inferred from Expression Pattern
more info
PubMed 
response to estradiol IEP
Inferred from Expression Pattern
more info
PubMed 
response to fatty acid IDA
Inferred from Direct Assay
more info
PubMed 
response to fatty acid IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to fatty acid ISO
Inferred from Sequence Orthology
more info
PubMed 
response to growth hormone IEP
Inferred from Expression Pattern
more info
PubMed 
response to linoleic acid ISO
Inferred from Sequence Orthology
more info
PubMed 
response to linoleic acid ISS
Inferred from Sequence or Structural Similarity
more info
 
response to lipid IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to lipid ISO
Inferred from Sequence Orthology
more info
PubMed 
response to mechanical stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to nutrient IEP
Inferred from Expression Pattern
more info
PubMed 
response to stilbenoid ISO
Inferred from Sequence Orthology
more info
PubMed 
sensory perception of taste ISO
Inferred from Sequence Orthology
more info
PubMed 
sensory perception of taste ISS
Inferred from Sequence or Structural Similarity
more info
 
triglyceride metabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
triglyceride transport ISO
Inferred from Sequence Orthology
more info
PubMed 
triglyceride transport ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
PubMed 
Golgi apparatus ISS
Inferred from Sequence or Structural Similarity
more info
 
apical part of cell IDA
Inferred from Direct Assay
more info
PubMed 
apical part of cell ISO
Inferred from Sequence Orthology
more info
PubMed 
apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 
brush border membrane IDA
Inferred from Direct Assay
more info
PubMed 
brush border membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
caveola IDA
Inferred from Direct Assay
more info
PubMed 
cell IEA
Inferred from Electronic Annotation
more info
 
cell ISO
Inferred from Sequence Orthology
more info
PubMed 
cell periphery ISO
Inferred from Sequence Orthology
more info
PubMed 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cell surface ISO
Inferred from Sequence Orthology
more info
PubMed 
endoplasmic reticulum IDA
Inferred from Direct Assay
more info
PubMed 
external side of plasma membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
membrane raft ISO
Inferred from Sequence Orthology
more info
PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
protein-containing complex IDA
Inferred from Direct Assay
more info
PubMed 
receptor complex ISO
Inferred from Sequence Orthology
more info
PubMed 
sarcolemma IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
platelet glycoprotein 4
Names
CD36 antigen (collagen type I receptor, thrombospondin receptor)
CD36 molecule (thrombospondin receptor)
Cd36 antigen-like
GPIIIB
GPIV
PAS IV
PAS-4
adipocyte membrane protein
collagen type I receptor thrombospondin receptor
fatty acid translocase
fatty acid transport protein
glycoprotein IIIb
platelet glycoprotein IV

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_031561.2NP_113749.2  platelet glycoprotein 4

    See identical proteins and their annotated locations for NP_113749.2

    Status: PROVISIONAL

    Source sequence(s)
    BC072543
    UniProtKB/TrEMBL
    Q6IMX5
    Related
    ENSRNOP00000069273.1, ENSRNOT00000091249.1
    Conserved Domains (1) summary
    pfam01130
    Location:16461
    CD36; CD36 family

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

    Range
    14150309..14191498
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000072.1 Alternate Rn_Celera

    Range
    12880238..12941086
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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