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Dsc2 desmocollin 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291760, updated on 21-Jul-2018

Summary

Official Symbol
Dsc2provided by RGD
Official Full Name
desmocollin 2provided by RGD
Primary source
RGD:1309426
See related
Ensembl:ENSRNOG00000039969
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Expression
Biased expression in Liver (RPKM 180.5), Heart (RPKM 79.2) and 7 other tissues See more

Genomic context

See Dsc2 in Genome Data Viewer
Location:
18p12
Exon count:
17
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 18 NC_005117.4 (11826705..11858801, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 18 NC_005117.3 (11625847..11658036, complement)

Chromosome 18 - NC_005117.4Genomic Context describing neighboring genes Neighboring gene desmocollin 3 Neighboring gene similar to Elongation factor 1-gamma (EF-1-gamma) (eEF-1B gamma) Neighboring gene desmocollin 1 Neighboring gene similar to apoptosis inhibitor 5

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Pathways from BioSystems

General gene information

Markers

Homology

Clone Names

  • MGC124744

Gene Ontology Provided by RGD

Function Evidence Code Pubs
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell-cell adherens junction IEA
Inferred from Electronic Annotation
more info
 
cell-cell adherens junction ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoplasmic vesicle ISO
Inferred from Sequence Orthology
more info
 
desmosome IEA
Inferred from Electronic Annotation
more info
 
desmosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intercalated disc IEA
Inferred from Electronic Annotation
more info
 
intercalated disc ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033688.1NP_001028860.1  desmocollin-2 precursor

    See identical proteins and their annotated locations for NP_001028860.1

    Status: PROVISIONAL

    Source sequence(s)
    BC101864
    UniProtKB/TrEMBL
    Q3T1K6
    Related
    ENSRNOP00000058135.4, ENSRNOT00000061417.4
    Conserved Domains (4) summary
    cd11304
    Location:247351
    Cadherin_repeat; Cadherin tandem repeat domain
    smart01055
    Location:31111
    Cadherin_pro; Cadherin prodomain like
    pfam00028
    Location:360462
    Cadherin; Cadherin domain
    pfam01049
    Location:853897
    Cadherin_C; Cadherin cytoplasmic region

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005117.4 Reference Rnor_6.0 Primary Assembly

    Range
    11826705..11858801 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008771935.2XP_008770157.1  desmocollin-2 isoform X1

    UniProtKB/TrEMBL
    A0A0G2K3I3
    Related
    ENSRNOP00000072649.1, ENSRNOT00000082891.1
    Conserved Domains (3) summary
    cd11304
    Location:247351
    Cadherin_repeat; Cadherin tandem repeat domain
    smart01055
    Location:31111
    Cadherin_pro; Cadherin prodomain like
    pfam00028
    Location:360462
    Cadherin; Cadherin domain

Alternate Rn_Celera

Genomic

  1. AC_000086.1 Alternate Rn_Celera

    Range
    11467743..11499764 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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