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Cartpt CART prepropeptide [ Rattus norvegicus (Norway rat) ]

Gene ID: 29131, updated on 10-Oct-2019

Summary

Official Symbol
Cartptprovided by RGD
Official Full Name
CART prepropeptideprovided by RGD
Primary source
RGD:2272
See related
Ensembl:ENSRNOG00000017712
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Cart
Summary
neuronal protein that may play a role in brain development and may be regulated by testosterone [RGD, Feb 2006]
Expression
Biased expression in Brain (RPKM 49.6) and Adrenal (RPKM 4.6) See more
Orthologs

Genomic context

See Cartpt in Genome Data Viewer
Location:
2q12
Exon count:
3
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (30125249..30127408, complement)
106 current Rn_Celera (GCF_000002265.2) 2 AC_000070.1 (27276402..27278422, complement)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 2 NC_005101.3 (49285118..49287405, complement)

Chromosome 2 - NC_005101.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102553999 Neighboring gene similar to ubiquitin-conjugating enzyme E2 variant 1 Neighboring gene methylcrotonoyl-CoA carboxylase 2 Neighboring gene B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
neuropeptide hormone activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
G protein-coupled receptor signaling pathway ISO
Inferred from Sequence Orthology
more info
PubMed 
activation of MAPKK activity IDA
Inferred from Direct Assay
more info
PubMed 
activation of MAPKK activity ISO
Inferred from Sequence Orthology
more info
PubMed 
adult feeding behavior IDA
Inferred from Direct Assay
more info
PubMed 
adult feeding behavior ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular glucose homeostasis ISO
Inferred from Sequence Orthology
more info
PubMed 
cellular glucose homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
 
cellular response to starvation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to starvation IDA
Inferred from Direct Assay
more info
PubMed 
cellular response to starvation ISO
Inferred from Sequence Orthology
more info
PubMed 
chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 
circadian regulation of gene expression IDA
Inferred from Direct Assay
more info
PubMed 
gastric acid secretion TAS
Traceable Author Statement
more info
PubMed 
negative regulation of appetite IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of appetite IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of appetite ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of bone resorption IEA
Inferred from Electronic Annotation
more info
 
negative regulation of bone resorption ISO
Inferred from Sequence Orthology
more info
PubMed 
negative regulation of glucagon secretion IDA
Inferred from Direct Assay
more info
PubMed 
neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 
positive regulation of blood pressure ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of blood pressure ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of epinephrine secretion ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of epinephrine secretion ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transmission of nerve impulse ISO
Inferred from Sequence Orthology
more info
PubMed 
positive regulation of transmission of nerve impulse ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of bone remodeling ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of insulin secretion IDA
Inferred from Direct Assay
more info
PubMed 
somatostatin secretion IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cell IEA
Inferred from Electronic Annotation
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
PubMed 
extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
 
secretory granule IEA
Inferred from Electronic Annotation
more info
 
secretory granule ISO
Inferred from Sequence Orthology
more info
PubMed 
synapse IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cocaine- and amphetamine-regulated transcript protein
Names
cocaine and amphetamine regulated transcript

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_017110.1NP_058806.1  cocaine- and amphetamine-regulated transcript protein precursor

    See identical proteins and their annotated locations for NP_058806.1

    Status: PROVISIONAL

    Source sequence(s)
    U10071
    UniProtKB/Swiss-Prot
    P49192
    Related
    ENSRNOP00000023869.1, ENSRNOT00000023869.2
    Conserved Domains (1) summary
    pfam06373
    Location:67129
    CART; Cocaine and amphetamine regulated transcript protein (CART)

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005101.4 Reference Rnor_6.0 Primary Assembly

    Range
    30125249..30127408 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006231843.3XP_006231905.1  cocaine- and amphetamine-regulated transcript protein isoform X1

    See identical proteins and their annotated locations for XP_006231905.1

    UniProtKB/Swiss-Prot
    P49192
    Conserved Domains (1) summary
    pfam06373
    Location:48116
    CART; Cocaine and amphetamine regulated transcript protein (CART)

Alternate Rn_Celera

Genomic

  1. AC_000070.1 Alternate Rn_Celera

    Range
    27276402..27278422 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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