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Aldh5a1 aldehyde dehydrogenase 5 family, member A1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 291133, updated on 21-Jul-2018

Summary

Official Symbol
Aldh5a1provided by RGD
Official Full Name
aldehyde dehydrogenase 5 family, member A1provided by RGD
Primary source
RGD:621422
See related
Ensembl:ENSRNOG00000023538
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Ssadh
Expression
Biased expression in Brain (RPKM 180.7), Liver (RPKM 165.7) and 9 other tissues See more
Orthologs

Genomic context

See Aldh5a1 in Genome Data Viewer
Location:
17p11
Exon count:
10
Annotation release Status Assembly Chr Location
106 current Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (42133076..42159413)
104 previous assembly Rnor_5.0 (GCF_000001895.4) 17 NC_005116.3 (44000875..44027212)

Chromosome 17 - NC_005116.4Genomic Context describing neighboring genes Neighboring gene magnesium transporter MRS2 Neighboring gene glycosylphosphatidylinositol specific phospholipase D1 Neighboring gene uncharacterized LOC103694089 Neighboring gene similar to mKIAA0319 protein Neighboring gene ribosomal protein L37, pseudogene 1 Neighboring gene tyrosyl-DNA phosphodiesterase 2

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Pathways from BioSystems

General gene information

Markers

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
NAD binding IDA
Inferred from Direct Assay
more info
PubMed 
carboxylic acid binding IPI
Inferred from Physical Interaction
more info
PubMed 
succinate-semialdehyde dehydrogenase (NAD+) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
succinate-semialdehyde dehydrogenase (NAD+) activity IDA
Inferred from Direct Assay
more info
PubMed 
succinate-semialdehyde dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 
succinate-semialdehyde dehydrogenase (NAD+) activity ISO
Inferred from Sequence Orthology
more info
 
succinate-semialdehyde dehydrogenase (NAD+) activity ISS
Inferred from Sequence or Structural Similarity
more info
 
succinate-semialdehyde dehydrogenase [NAD(P)+] activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
succinate-semialdehyde dehydrogenase [NAD(P)+] activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acetate metabolic process IEA
Inferred from Electronic Annotation
more info
 
acetate metabolic process ISO
Inferred from Sequence Orthology
more info
 
central nervous system development IEA
Inferred from Electronic Annotation
more info
 
central nervous system development ISO
Inferred from Sequence Orthology
more info
 
central nervous system development ISS
Inferred from Sequence or Structural Similarity
more info
 
central nervous system development TAS
Traceable Author Statement
more info
PubMed 
galactosylceramide metabolic process IEA
Inferred from Electronic Annotation
more info
 
galactosylceramide metabolic process ISO
Inferred from Sequence Orthology
more info
 
gamma-aminobutyric acid catabolic process IEA
Inferred from Electronic Annotation
more info
 
gamma-aminobutyric acid catabolic process ISO
Inferred from Sequence Orthology
more info
 
gamma-aminobutyric acid catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
gamma-aminobutyric acid catabolic process TAS
Traceable Author Statement
more info
PubMed 
gamma-aminobutyric acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 
glucose metabolic process ISO
Inferred from Sequence Orthology
more info
 
glucosylceramide metabolic process IEA
Inferred from Electronic Annotation
more info
 
glucosylceramide metabolic process ISO
Inferred from Sequence Orthology
more info
 
glutamate metabolic process IEA
Inferred from Electronic Annotation
more info
 
glutamate metabolic process ISO
Inferred from Sequence Orthology
more info
 
glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
 
glutamine metabolic process ISO
Inferred from Sequence Orthology
more info
 
glutathione metabolic process IEA
Inferred from Electronic Annotation
more info
 
glutathione metabolic process ISO
Inferred from Sequence Orthology
more info
 
glycerophospholipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
glycerophospholipid metabolic process ISO
Inferred from Sequence Orthology
more info
 
neurotransmitter catabolic process ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process IDA
Inferred from Direct Assay
more info
PubMed 
post-embryonic development IEA
Inferred from Electronic Annotation
more info
 
post-embryonic development ISO
Inferred from Sequence Orthology
more info
 
protein homotetramerization IEA
Inferred from Electronic Annotation
more info
 
protein homotetramerization ISO
Inferred from Sequence Orthology
more info
 
respiratory electron transport chain IEA
Inferred from Electronic Annotation
more info
 
respiratory electron transport chain ISO
Inferred from Sequence Orthology
more info
 
short-chain fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
short-chain fatty acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
succinate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
succinate metabolic process IEA
Inferred from Electronic Annotation
more info
 
succinate metabolic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion IEA
Inferred from Electronic Annotation
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
mitochondrion ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
succinate-semialdehyde dehydrogenase, mitochondrial
Names
NAD(+)-dependent succinic semialdehyde dehydrogenase
aldehyde dehydrogenase 5 family, member A1 (succinate-semialdehyde dehydrogenase)
aldehyde dehydrogenase family 5, subfamily A1
succinic semialdehyde dehydrogenase
NP_074042.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022851.1NP_074042.1  succinate-semialdehyde dehydrogenase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_074042.1

    Status: VALIDATED

    Source sequence(s)
    AABR07027718, FM032642
    UniProtKB/TrEMBL
    G3V945
    Related
    ENSRNOP00000035601.3, ENSRNOT00000031384.5
    Conserved Domains (1) summary
    TIGR01780
    Location:66516
    SSADH; succinate-semialdehyde dehydrogenase

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Rnor_6.0 Primary Assembly

Genomic

  1. NC_005116.4 Reference Rnor_6.0 Primary Assembly

    Range
    42133076..42159413
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Rn_Celera

Genomic

  1. AC_000085.1 Alternate Rn_Celera

    Range
    39769869..39796199
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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